Innovation and Partnerships Office

Remote NMR/MRI Detection IB-1771

Low field encoding High field detection = better sensitivity
APPLICATIONS:

Enhanced sensitivity expands the uses of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) to:

  • Minute sample quantities
  • Low concentrations
  • Environments not conducive to conventional NMR
1771remoteleft ––––––––– > travel time:
~5 meters in ~ 15 seconds
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ADVANTAGES:

  • Conditions for encoding can be manipulated independently from those for detection, optimizing both procedures
  • Broadens NMR/MRI applications by utilizing the myriad encoding features of NMR while introducing alternative and sensitive detection techniques
  • Employs non-penetrating detection methods

ABSTRACT:

Berkeley Lab’s remote NMR/MRI detection invention allows for independent manipulation of encoding and detection conditions so that experimental and technical parameters can be adjusted to optimize both processes.

Alexander Pines
and colleagues have invented a technique that allows the NMR/MRI signal of any gas or liquid having a long polarization relaxation time to be prepared in one location and detected in another. The signal can be remotely detected by an array of ultrasensitive techniques so as to reconstruct images and spectra yielding spatial distributions and molecular compositions. The signal information can be encoded in the longitudinal magnetization of 129xenon, for example, which has been used extensively to characterize surfaces and cavities in porous materials and biological systems.

This new Berkeley Lab method makes accessible spatial and spectroscopic information about minute sample quantities or samples encoded in very low magnetic fields. It includes optimized rf coil detection and the possibility of using ultrasensitive techniques like SQUIDs and optical devices in addition to conventional NMR detection.

STATUS:

  • U.S. Patent Application #7,061,237. Available for licensing or collaborative research

FOR MORE INROMATION PLEASE SEE:

http://www.lbl.gov/Science-Articles/Archive/MSD-remote-detection-MRI.html

 

REFERENCE NUMBER: IB-1771

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