Published July 22, 2026

Summary: This technology pretreats plant biomass using aqueous dimethylamine at room temperature. It eliminates heating, making biofuel and bioproduct production more energy-efficient and cost-effective, while yielding high amounts of fermentable sugars.

Applications: 

  • Biorefinery feedstock pretreatment
  • Biodiesel, bio-oil, lignin production
  • Sustainable paper pulping

Advantages/Benefits: 

  • Low energy consumption
  • High fermentable sugar yields
  • Industrial scalability
  • Versatile bioproduct applications

Background: Dimethylamine is a potent reagent for the pretreatment of lignocellulosic biomass in aqueous solutions, but requires processing at elevated temperatures. 

Technology Overview: 

Scientists at Berkeley Lab have developed a method for pretreating lignocellulosic biomass using aqueous dimethylamine effectively at room temperature. This process eliminates the energy input typically required for heating by allowing biomass to rest with the solution for extended periods. It maintains chemical reactivity for high yields of fermentable sugars and is scalable for biorefineries, biomass saponification, and alternative paper pulping.

This technology is differentiated by its ability to operate entirely at ambient conditions, a significant departure from conventional methods that demand elevated temperatures. This key innovation eliminates the need for thermal energy input, substantially reducing operational costs and complexity, making it a more sustainable and economically viable solution. The method achieves over 80% glucose and xylose yields after 12 hours.

Development Stage: TRL 6 – Prototypical system validation

Inventors:

Joseph Palasz

Anagha Krishnamoorthy

Xueli Chen

Blake Simmons

Status: Patent pending

Opportunities: Available for licensing and / or collaborative research