APPLICATIONS OF TECHNOLOGY: DNA synthesis ABSTRACT: Oligonucleotides are almost exclusively synthesized using the nucleoside phosphoramidite method, even though it is limited to the direct synthesis of ~200 mers and produces hazardous waste. Researchers at the Joint BioEnergy Institute (JBEI) have developed an oligonucleotide synthesis strategy that uses the … [Read more...] about DNA Synthesis Using Tethered dNTPs 2018-103
Biotechnology and Medicine
ANIcalculator (Average Nucleotide Identity Calculator) 2014-127
APPLICATIONS OF TECHNOLOGY: Genome sequencing ABSTRACT: Increased sequencing of microbial genomes has revealed that prevailing prokaryotic species assignments can be inconsistent with whole genome information for a significant number of species. The long-standing need for a systematic and scalable species assignment technique can be met by the genome-wide Average … [Read more...] about ANIcalculator (Average Nucleotide Identity Calculator) 2014-127
HOPO Ligands to Separate and Purify Metal Ions including Lanthanides and Actinides 2017-106
APPLICATIONS OF TECHNOLOGY: Nuclear energy or nuclear fuel reprocessing plants Pharmaceutical isotope production Pharmaceutical companies using lanthanide or actinide drugs Chemical industry ADVANTAGES: Greater separation efficacy Robust chelators Highly versatile method Simplified process ABSTRACT: Berkeley Lab researchers Rebecca Abergel … [Read more...] about HOPO Ligands to Separate and Purify Metal Ions including Lanthanides and Actinides 2017-106
Selective Complexation and Separation of Tetravalent Metal Ions from Other Ions 2017-107
APPLICATIONS OF TECHNOLOGY: Nuclear energy or nuclear fuel reprocessing plants Pharmaceutical isotope production Pharmaceutical companies using lanthanide or actinide drugs Chemical industry ADVANTAGES: Highly selective Improved performance and reliability Versatile process Fewer steps ABSTRACT: Berkeley Lab researchers Rebecca Abergel and … [Read more...] about Selective Complexation and Separation of Tetravalent Metal Ions from Other Ions 2017-107
Thermostable RNA-Guided Endonucleases (GEOCAS9) 2017-117
APPLICATIONS OF TECHNOLOGY: Genome editing Genetic engineering Gene therapy Research tools (e.g., high-throughput screening of gene functions in cell lines and in vivo) Creation of transgenic animal models ADVANTAGES: Functions under different conditions than current CRISPR-Cas9 proteins (e.g, thermostable and enzymatically active in a wide temperature … [Read more...] about Thermostable RNA-Guided Endonucleases (GEOCAS9) 2017-117
