APPLICATIONS OF TECHNOLOGY: Combined use with contemporary gene editing technologies for high precision gene expression Utilization of novel transcription factor effector domain activators to regulate gene expression in multiple hosts including plants and microbes BENEFITS: Method of metabolic and genome engineering using underutilized transcription factor … [Read more...] about Synthetic transcription factor systems for enhanced control of gene expression 2021-082
Agriculture
Engineered bacteria for enhanced crop production 2021-108
APPLICATIONS OF TECHNOLOGY: Dramatic enhancement of crop yields in agriculture applications though direct microbial application BENEFITS: Increased crop biomass (Arabidopsis) yield by 250-500% both in normal and drought conditions Enhanced durability and survivability in different environments Combined plant growth-promoting traits including growth promotion … [Read more...] about Engineered bacteria for enhanced crop production 2021-108
EcoBOT-Automated Platform for EcoFAB Experiments 2022-042
APPLICATIONS OF TECHNOLOGY: EcoBOT automates multiple simultaneous sterile biological experiments. It screens novel plant amendments for effectiveness under various conditions and for potential biohazards. It consistently identifies the impact of various amendments on plant root and leaf traits at various stages of growth. It can parse the effects of multiple … [Read more...] about EcoBOT-Automated Platform for EcoFAB Experiments 2022-042
Chelator-Mediated Fenton (CMF) Process to Transform Lignin into a Water-Soluble Polymer without Need for Separation or Concentration Steps 2019-152, 2019-054, 2021-042
APPLICATIONS OF TECHNOLOGY: Generation of polymer products from lignin (e.g., lignosulfonate polymer products) Dispersants, water-purification agents, water-adsorbing materials, and soil amendment BENEFITS: CMF lignin is likely to be produced at lower cost compared to prior approach using polyacrylic based materials Process generates less hazardous waste or … [Read more...] about Chelator-Mediated Fenton (CMF) Process to Transform Lignin into a Water-Soluble Polymer without Need for Separation or Concentration Steps 2019-152, 2019-054, 2021-042
High-Throughput Protein Pull-Down for Mapping Transcription Factors, “Biotin DAP-seq” 2021-071
APPLICATIONS OF TECHNOLOGY: Translation of DNA sequences into affinity labeled proteins Protein isolation for downstream characterization For application in transcription factor (TF) binding site discovery methods (e.g., DAP-seq, SELEX), RNA protein-binding site discovery, and protein-protein interaction studies BENEFITS: This method is equally effective, … [Read more...] about High-Throughput Protein Pull-Down for Mapping Transcription Factors, “Biotin DAP-seq” 2021-071