Applications: Increased protein expression yields in plants and fungi Development of drought-resistant crops Streamlined method to develop new genetic tools and genome-scale activation assays Advantages: Equal or stronger activity than the current state of the art activation domains Quick integration of regulatory domains into known and novel expression … [Read more...] about Novel Transcriptional Activator Domains from Plants and Yeast To Enhance Eukaryotic Gene Expression 2023-135
Human Health/Precision Medicine
High-precision Pipette Tips Compatible with Existing Liquid Handling Robots 2023-014
APPLICATIONS OF TECHNOLOGY: Mass spectrometry High-density microarray applications Food and pharmaceutical laboratory research BENEFITS: Rapid and accurate high-throughput testing More repeatable than manual pipetting Ensures more efficient and complete sample transfer Reduced risk of sample loss or contamination Ability to interface with existing … [Read more...] about High-precision Pipette Tips Compatible with Existing Liquid Handling Robots 2023-014
Genetically Modified Host Cells for Improved Polyketide Production 2022-152
APPLICATIONS OF TECHNOLOGY: High-value products using methylmalonyl-CoA as substrate: Erythromycin (antibiotic) and spinosyn (insecticide) Germicidin, which has significant inhibitory activity on hexokinase which is expressed at a high level in cancer cells Novel recyclable materials Flavors and fragrances Commodity or specialty chemicals ADVANTAGES: … [Read more...] about Genetically Modified Host Cells for Improved Polyketide Production 2022-152
Chelating Ligands for Enhanced Radiolabeling and Therapeutic Potential 2023-119
APPLICATIONS OF TECHNOLOGY: Development of radiopharmaceuticals for cancer diagnosis and treatment Development of antibodies labeled with radionuclides BENEFITS: Simplified synthesis compared to other structures Faster radiolabeling at room temperature Formation of highly stable radiometal complexes Higher synthetic yields BACKGROUND: Thorium-227 … [Read more...] about Chelating Ligands for Enhanced Radiolabeling and Therapeutic Potential 2023-119
Imaging and Analysis Technologies
Novel Fluidic System for Accurate High Speed Atomic Force Microscopy (AFM) and Confocal/Super Resolution Systems 2021-020 This invention provides improved timing and concentration precision compared to current fluidic exchange designs. This tool is ideal for those conducting microscopy-based studies of reaction kinetics. Inventor: Paul Ashby. Contact: Sebastian Ainslie, … [Read more...] about Imaging and Analysis Technologies