APPLICATIONS: Genomics research BACKGROUND: Metabolomics has been used for obtaining direct measures of metabolic activities from diverse biological systems. However, metabolomics can be limited by ambiguous metabolite identifications. Furthermore, interpretation can be limited by incomplete and inaccurate genome-based predictions of enzyme activities (e.g., gene … [Read more...] about Metabolite, Annotation and Gene Integration System (MAGI) and Software 2017-063, 2017-105
Research
Improving High Value Carotenoid Astaxanthin Production 2017-033
APPLICATIONS OF TECHNOLOGY: Human health and nutrition Biofuel feedstocks Food production ADVANTAGES: More economically viable means to produce microalgae Identifies specific genes required for astaxanthin antioxidant synthesis ABSTRACT: Researchers led by Melissa Roth of Howard Hughes Medical Institute and Krishna Niyogi of the Berkeley Lab have … [Read more...] about Improving High Value Carotenoid Astaxanthin Production 2017-033
Self-Assembling Protein Nanocage decorated with Antibodies (SAPNA) 2018-075
APPLICATIONS OF TECHNOLOGY: Biopharmaceuticals Cancer immunotherapy ADVANTAGES: Capable of interchanging antibodies, therefore, multi-functional Modular, available for use by human IgG1 and rabbit IgG antibodies Potential uses increase as more monoclonal antibody products developed ABSTRACT: Researchers at the Berkeley Lab have developed a … [Read more...] about Self-Assembling Protein Nanocage decorated with Antibodies (SAPNA) 2018-075
In vitro Assembly, Adhering Cargo to Bacterial Microcompartment (BMC) Shells 2017-131, 2016-150
APPLICATIONS OF TECHNOLOGY: Enables health care, industrial and other commercial uses of protein-based bacterial organelles (bacterial microcompartments (BMCs)) ADVANTAGES: Modular system for 2- and 3-dimensional scaffolds/compartments Defined composition, atomic-resolution structure known Robust, programmable encapsulation or polyvalent display of multiple … [Read more...] about In vitro Assembly, Adhering Cargo to Bacterial Microcompartment (BMC) Shells 2017-131, 2016-150
Probiotics to Convey Resistance to Pesticide Poisoning 2017-083
APPLICATIONS OF TECHNOLOGY: Agriculture Pesticide resistance ADVANTAGES: Protects against toxic environmental chemicals Expands the metabolic potential of an individual’s microbiome for detoxification ABSTRACT: Berkeley Lab researchers led by Susan Celniker, Ben Brown, and Ken Wan have developed a technology to address pesticide sensitivity in … [Read more...] about Probiotics to Convey Resistance to Pesticide Poisoning 2017-083