APPLICATIONS OF TECHNOLOGY: Phage engineering Cataloging and Control of phages Diagnosis and Antibiotic Discovery ADVANTAGES: No interference of the phage infection cycle No compromise of the host bacteria life cycle Enables easy amplification of the DNA “barcode” for identification, tracking and control of individual phages Standardizes the workflow … [Read more...] about Novel Methods for the Barcoding of Bacteriophages 2019-113
Therapeutics
Gut Microbiome Engineering for the Heterologous Production of Antiviral Compounds 2019-085
APPLICATIONS OF TECHNOLOGY: Medical: Pharmaceuticals ADVANTAGES: Present strain is among the most robust constituents of the gut microbiome Obviates the need for exogenous iron-sulfur cluster producing genetic elements ABSTRACT: In 2018, Gizzi et al. demonstrated that the human gene Viperin can produce antiviral small molecules (ddhCTP) that act as a chain … [Read more...] about Gut Microbiome Engineering for the Heterologous Production of Antiviral Compounds 2019-085
Polysaccharide Gel 2017-041
APPLICATIONS OF TECHNOLOGY: Food products Cosmetics Water and wastewater treatment Pharmaceuticals BENEFITS: Significantly lowers the costs of product recovery from cyanobacterial production strains Self-aggregating properties of the material streamline the processes of flocculation and clarification Enables novel encapsulation and drug formulation … [Read more...] about Polysaccharide Gel 2017-041
Peptoid-Based Chelating Molecules 2017-181
APPLICATIONS OF TECHNOLOGY: Radiolabeling Metal separation Water treatment ADVANTAGES: Robust chelators High selectivity ABSTRACT: Researchers led by Rebecca Abergel have developed a new class of chelators – molecules that can bind metals – that incorporate peptoids into the chelator backbone, offering more control over the chelator’s structure and … [Read more...] about Peptoid-Based Chelating Molecules 2017-181
High-Throughput Methods to Characterize Phage Receptors and Rational Formulation of Phage Cocktails 2019-048
APPLICATIONS OF TECHNOLOGY: Pharmaceutical / antibiotic discovery Phage therapy ADVANTAGES: Compared to current technologies Less expensive Less laborious Scalable Quantitative ABSTRACT: Researchers at the Berkeley Lab have developed two genetic technologies that enable fast and effective genome-wide screens for gene function. The LBNL … [Read more...] about High-Throughput Methods to Characterize Phage Receptors and Rational Formulation of Phage Cocktails 2019-048