Applications of Technology: High production volume of biosynthesis products such as nylons and fuels while consuming less sugar feedstock Advantages: Dramatically increased efficiency in use of fuel due to no CO2 emission during glycolysis. 50% increase in maximum theoretical yield. Reduced gas buildup from biosynthesis tasks. This strain does not require … [Read more...] about Engineered Escherichia coli Strain with Non-Oxidative Glycolysis for Increased Carbon Use Efficiency and Reduced Gas Emissions 2022-147
Synthetic Biology Tools and Software
Novel Transcriptional Activator Domains from Plants and Yeast To Enhance Eukaryotic Gene Expression 2023-135
Applications: Increased protein expression yields in plants and fungi Development of drought-resistant crops Streamlined method to develop new genetic tools and genome-scale activation assays Advantages: Equal or stronger activity than the current state of the art activation domains Quick integration of regulatory domains into known and novel expression … [Read more...] about Novel Transcriptional Activator Domains from Plants and Yeast To Enhance Eukaryotic Gene Expression 2023-135
Host Cell for Production of Mevalonate (Precursor for Sustainable Aviation Fuel) from Syngas 2024-043
Applications Sustainable aviation fuel (SAF) production of mevalonate Fragrance production from syngas or industrial off-gases Advantages/Benefits Increased energy efficiency from utilizing an aerobic host for bioconversion Improved facilitation of synthesis of complex molecules Versatile usage in various industries, including biofuels and … [Read more...] about Host Cell for Production of Mevalonate (Precursor for Sustainable Aviation Fuel) from Syngas 2024-043
Multiple Binary Vector Packing to Improve Plant Metabolic Engineering 2024-046
Applications Enhanced metabolism and expression of complex metabolites in plants Improved yields of complex molecules in target host cells Production of valuable compounds, such as pharmaceuticals and biofuels Advantages/Benefits Increased transformation efficiency and target molecule production Predictive quantitative model to aid in experimental design … [Read more...] about Multiple Binary Vector Packing to Improve Plant Metabolic Engineering 2024-046
NovaDemux Software: Error-Tolerant Sequence Demultiplexer for Increased Yield of DNA Sequencing Machines 2024-089, 2024-091
APPLICATIONS OF TECHNOLOGY: Any application that involves using DNA sequencing machines. BENEFITS: Allow substantial increase in yield of DNA sequencing machines without increasing crosstalk BACKGROUND: For genetic sequencing, DNA from an actual genome is tagged with a synthetic barcode. This allows multiple experiments from many sources to be physically pooled … [Read more...] about NovaDemux Software: Error-Tolerant Sequence Demultiplexer for Increased Yield of DNA Sequencing Machines 2024-089, 2024-091