APPLICATIONS OF TECHNOLOGY: Design of novel proteins with a specified set of properties or functions Modification of properties of existing proteins Inference of the function of protein sequences BACKGROUND: Challenges in protein design include: not every protein sequence encodes a functional protein, and there is an underlying syntax to folding protein … [Read more...] about A Model for Generating Protein Sequences for Protein Design or Phenotypic Inference 2019-045
Synthetic Biology Tools and Software
2023-051 High-Titer and Highly Specific Prenol Production in Microbial Hosts via the Pathway using Recombinant Kinases and Isomerases
Applications Biofuel additive for enhanced gasoline blending properties. Chemical precursor for the production of prenyl acetate and other industrial compounds. Environmentally friendly alternative to petrochemicals in biofuel production. Advantages/Benefits Produces high-purity prenol with minimal byproducts, enabling cleaner production Avoids toxic … [Read more...] about 2023-051 High-Titer and Highly Specific Prenol Production in Microbial Hosts via the Pathway using Recombinant Kinases and Isomerases
Method for Producing Luminescent Protein Shells 2025-005
Applications Molecular diagnostics Nanofactory engineering Advanced light-emitting materials Advantages/Benefits More controlled and better measurement of membrane permeability Enhanced stability and longevity of protein particles Background Biotechnology relies on luminescent luciferase enzymes for applications such as quantifying gene expression … [Read more...] about Method for Producing Luminescent Protein Shells 2025-005
Novel engineered immune receptor to protect rice from pathogens 2023-147
Applications Sustainable crop protection against rice blast disease Usage in genetic modification/genome editing to develop disease-resistant rice varieties Potential for use in other crops to protect against similar fungal diseases Advantages/Benefits Wider range of protection than existing blast resistance genes against Magnaporthe oryzae strains … [Read more...] about Novel engineered immune receptor to protect rice from pathogens 2023-147
Engineered Escherichia coli Strain with Non-Oxidative Glycolysis for Increased Carbon Use Efficiency and Reduced Gas Emissions 2022-147
Applications of Technology: High production volume of biosynthesis products such as nylons and fuels while consuming less sugar feedstock Advantages: Dramatically increased efficiency in use of fuel due to no CO2 emission during glycolysis. 50% increase in maximum theoretical yield. Reduced gas buildup from biosynthesis tasks. This strain does not require … [Read more...] about Engineered Escherichia coli Strain with Non-Oxidative Glycolysis for Increased Carbon Use Efficiency and Reduced Gas Emissions 2022-147