APPLICATIONS OF TECHNOLOGY: Targeted cancer therapies Prediction of relapse-free survival ADVANTAGES: Determines most effective treatment options for patient quality of life Standardizes breast cancer prognoses ABSTRACT: A Berkeley Lab research team led by Antoine Snijders has identified a 12-gene signature that can be used to predict relapse-free … [Read more...] about A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
Cancer Prognostics
A Long Non-Coding RNA Expressed in Aggressive Cancer 2014-109
ABSTRACT Berkeley Lab researchers have developed technologies to evaluate levels of the long, non-coding RNA to assess the aggressiveness of a cancer and to modulate levels of the long non-coding RNA. This invention addresses the need to identify patients with potentially metastatic tumors versus non-metastatic tumors. For more details, see Published PCT patent … [Read more...] about A Long Non-Coding RNA Expressed in Aggressive Cancer 2014-109
Centromere/Kinetochore Protein Genes for Cancer Prognosis, Diagnosis, and Treatment 2013-163
Based on a signature of 21 CEN/KT genes demonstrated to be linked to the progression of many different types of cancers, this technology has the potential to identify early stage patients at high risk for disease progression, predict survival prognosis and the risk of metastatic relapse for patients being treated for multiple cancers at various pathological stages, and predict … [Read more...] about Centromere/Kinetochore Protein Genes for Cancer Prognosis, Diagnosis, and Treatment 2013-163
Genetic Barcodes for Cancer Prediction and Prognosis IB-2897
APPLICATIONS OF TECHNOLOGY: Cancer diagnostics and therapy ADVANTAGES: Fast, accurate, and affordable Improves tumor staging and patient stratification for most cancers ABSTRACT: Berkeley Lab researcher Heinz-Ulrich Weier has developed Genetic Barcodes, a fluorescent in situ hybridization (FISH)-based assay offering affordable diagnostics for the early … [Read more...] about Genetic Barcodes for Cancer Prediction and Prognosis IB-2897
Increased Glucose Metabolism is Oncogenic; Its Reversal May Be Therapeutic IB-2921
APPLICATIONS OF TECHNOLOGY: Cancer diagnostics Cancer therapeutics Cancer research ADVANTAGES: Provides markers correlated with increased metastases risk Provides for therapies that block or reverse cancer progression through adjusting glucose metabolism ABSTRACT: Berkeley Lab researchers led by Mina Bissell … [Read more...] about Increased Glucose Metabolism is Oncogenic; Its Reversal May Be Therapeutic IB-2921