APPLICATIONS OF TECHNOLOGY: Targeted cancer therapies Prediction of relapse-free breast cancer survival ADVANTAGES: Determines most effective treatment options for patient quality of life Standardizes breast cancer prognoses ABSTRACT: Berkeley Lab researchers Jian-Hua Mao and Antoine Snijders have identified a unique set of seven genes for Luminal A … [Read more...] about Gene Signatures Predict Survival Benefit from Radiotherapy in Patients with Luminal A and Basal Type Breast Cancers 2017-037
Cancer Prognostics
A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
APPLICATIONS OF TECHNOLOGY: Targeted cancer therapies Prediction of relapse-free survival ADVANTAGES: Determines most effective treatment options for patient quality of life Standardizes breast cancer prognoses ABSTRACT: A Berkeley Lab research team led by Antoine Snijders has identified a 12-gene signature that can be used to predict relapse-free … [Read more...] about A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
A Long Non-Coding RNA Expressed in Aggressive Cancer 2014-109
ABSTRACT Berkeley Lab researchers have developed technologies to evaluate levels of the long, non-coding RNA to assess the aggressiveness of a cancer and to modulate levels of the long non-coding RNA. This invention addresses the need to identify patients with potentially metastatic tumors versus non-metastatic tumors. For more details, see Published PCT patent … [Read more...] about A Long Non-Coding RNA Expressed in Aggressive Cancer 2014-109
Centromere/Kinetochore Protein Genes for Cancer Prognosis, Diagnosis, and Treatment 2013-163
Based on a signature of 21 CEN/KT genes demonstrated to be linked to the progression of many different types of cancers, this technology has the potential to identify early stage patients at high risk for disease progression, predict survival prognosis and the risk of metastatic relapse for patients being treated for multiple cancers at various pathological stages, and predict … [Read more...] about Centromere/Kinetochore Protein Genes for Cancer Prognosis, Diagnosis, and Treatment 2013-163
High Resolution Digital Autoradiography IB-2959
APPLICATIONS OF TECHNOLOGY: Medical diagnostics Biological research involving localization and measurement of radiotracers ADVANTAGES: Higher pixel (to 10 µm) and spatial resolution imaging than previously possible Real time autoradiography Able to detect a wide variety of tracers (e.g., 11C, 14C, 18F, 3H) Able to image β- and β+ simultaneously (dual-tracer … [Read more...] about High Resolution Digital Autoradiography IB-2959