APPLICATIONS OF TECHNOLOGY: Combinatorial screening in Drug discovery and optimization Biomanufacturing Diagnostics ADVANTAGES: Enables faster testing of more diverse conditions / combinations Readily detects lanthanide/chelator complexes Maintains strong lanthanide binding and single-charge ionization Simplified … [Read more...] about Lanthanide-Chelator Barcode for Combinatorial Screening Applications 2016-121
Technologies and Software
Precise, High Throughput Droplet Manipulation 2013-128
APPLICATIONS: Research – pharmaceutical, enzyme, genetics ADVANTAGES: Can screen an extremely large number of biological samples Capable of evaluating multiple experimental conditions at one time Generates droplets quickly and efficiently based on various characteristics Utilizes new and effective droplet mixing and sorting … [Read more...] about Precise, High Throughput Droplet Manipulation 2013-128
Producing Antibiotics with Growth-Arrested Cells 2014-061
APPLICATIONS OF TECHNOLOGY: Antibiotic production on an industrial scale ADVANTAGES: May lower the production costs of compounds that are only cost-effective to produce using synthetic chemistry May increase production titers ABSTRACT: Researchers at the Joint BioEnergy Institute (JBEI) have developed an affordable method to produce a diverse arsenal of … [Read more...] about Producing Antibiotics with Growth-Arrested Cells 2014-061
Library of Plasmids to Control Gene Expression Levels EIB-2792
APPLICATIONS OF TECHNOLOGY: Biofuel production Pharmaceutical and chemical production Biological research involving gene expression ADVANTAGES: Enables control over gene expression Applicable with any genes lacking 4 particular restriction sites ABSTRACT: Taek Soon Lee and colleagues at the Joint BioEnergy Institute (JBEI) have developed a technology that … [Read more...] about Library of Plasmids to Control Gene Expression Levels EIB-2792
Rapid Discovery and Optimization of Enzyme Solutions Using Tagged Biomass and Mass Spectrometry EJIB-3262
APPLICATIONS Biofuel production Glycobiology Drug discovery Enzyme bioengineering ADVANTAGES Allows native substrates to screen for specific enzymatic activities Small sample volume, high throughput Potential to aid explanation of enzyme catalytic mechanism ABSTRACT Creating optimal enzymes to improve the efficiency of converting biomass into sugars … [Read more...] about Rapid Discovery and Optimization of Enzyme Solutions Using Tagged Biomass and Mass Spectrometry EJIB-3262