APPLICATIONS OF TECHNOLOGY: Production of the following from sugar or starch: Dicarboxylic acids Diacids Biotin Precursors to isooctane ADVANTAGES: Sustainable replacement for products currently derived from petroleum Flexibility to achieve material properties not otherwise possible Lower production costs ABSTRACT: Researchers at the Joint … [Read more...] about JBEI Polyketide Synthases Portfolio for Production of Chemicals and Fuels EJIB-2820, EJIB-2825, EIB-2878, EJIB-2982, EJIB-3014
Bio-based products
Introduction of a Synthetic CO2-fixing Photorespiratory Bypass into a Cyanobacterium 2013-020
ABSTRACT: Global photosynthetic productivity is limited by the enzymatic assimilation of CO2 into organic carbon compounds. Ribulose-1,5- bisphosphate carboxylase/oxygenase (RuBisCO), the carboxylating enzyme of the Calvin-Benson (CB) cycle, poorly discriminates between CO2 and O2, leading to photorespiration and the loss of fixed carbon and nitrogen. With the advent of … [Read more...] about Introduction of a Synthetic CO2-fixing Photorespiratory Bypass into a Cyanobacterium 2013-020
Enhanced Production of Biofuel Precursors in Microalgae 2013-075
APPLICATIONS OF TECHNOLOGY: Oil / biodiesel production Algal strain improvement and targeted engineering Agriculture industries Biotech research, e.g. identifying master regulators for stress-elicited responses ADVANTAGES: Simultaneously maximizes both algal growth and lipid accumulation Covers large numbers of genes in multiple pathways ABSTRACT: A … [Read more...] about Enhanced Production of Biofuel Precursors in Microalgae 2013-075
Production of Fatty-Acid-Derived Biofuels and Chemicals in Saccharomyces cerevisiae 2013-113
APPLICATIONS OF TECHNOLOGY: Green source of Biofuels Polymers Lubricants Cosmetics, flavors, fragrances Pharmaceuticals ADVANTAGES: S. cerevisiae more genetically tractable than microalgae or oleaginous yeast Mutant strains easy to generate, isolate, analyze Proven track record of S. cerevisiae in industrial applications Readily … [Read more...] about Production of Fatty-Acid-Derived Biofuels and Chemicals in Saccharomyces cerevisiae 2013-113
Efflux Pumps to Increase Microbial Tolerance and Biofuel Production EIB-2845
APPLICATIONS OF TECHNOLOGY: Biofuels Chemicals Pharmaceuticals ADVANTAGES: Increases production yield Improves economic viability of biological / renewable production Applicable in various host organisms for a wide range of compounds ABSTRACT: Aindrila Mukhopadhyay, Jay Keasling, and Mary Dunlop at the Joint BioEnergy Institute (JBEI) have developed a … [Read more...] about Efflux Pumps to Increase Microbial Tolerance and Biofuel Production EIB-2845