Engineering S. cerevisiae to Produce Isoprenol for Sustainable Aviation Fuel and Chemicals 2020-086 This invention incorporates both the original mevalonate pathway and isopentenyl diphosphate-bypass pathway for isoprenol production. By constructing a knockout strain of a key endogenous gene, the strain achieved 380 mg/L titer. Inventors: Taek Soon Lee, Jinho … [Read more...] about Biomanufacturing Technologies & Tools
Bio-based products
Engineering Osteoyeast for the Production of Calcium Phosphate-Based Composite Biomaterials 2021-099
APPLICATIONS OF TECHNOLOGY: Hydroxyapatite (HAP) production for use in dental and bone reconstruction, water purification, and compound materials for construction or for packaging BENEFITS: Cost effective production of HAP and HAP-based composites Microbial production method allows shorter processing times and higher degrees of control BACKGROUND: … [Read more...] about Engineering Osteoyeast for the Production of Calcium Phosphate-Based Composite Biomaterials 2021-099
Production of 4-Vinylphenol for Bioplastics 2021-122
APPLICATIONS OF TECHNOLOGY: Manufacture of soft plastics BENEFITS: Offers the possibility to achieve high 4-vinylphenol (4VP) titers from high-substrate batch cultures with minimal intervention Higher compatibility of undecanol may increase the number of organisms that can be employed for this and other related processes, which could diversify the range of … [Read more...] about Production of 4-Vinylphenol for Bioplastics 2021-122
Systematic Engineering of Methylomicrobium alcaliphilum Strain for Production of Rhamnolipid (RLs) Biosurfactants 2019-167
APPLICATIONS OF TECHNOLOGY: Oil recovery, bioremediation, crop protection, cosmetics, and pharmaceuticals BENEFITS: Rhamnolipids (RLs) are industrially well known surfactants, so far only produced by biological routes from sugar. Engineered M. alcaliphilum strain DASS can convert waste-greenhouse gas, methane to rhamnolipids without addition of sugars and other … [Read more...] about Systematic Engineering of Methylomicrobium alcaliphilum Strain for Production of Rhamnolipid (RLs) Biosurfactants 2019-167
Plasmid Library for Fatty Alcohol Production by Cupriavidus Necator 2022-028
APPLICATIONS OF TECHNOLOGY: Industrial detergents and surfactants Sustainable biofuel production BENEFITS: Can be made from H2/CO2 Genes regulated by synthetic graded ribosomal binding sites (RBSs) BACKGROUND: Fatty alcohols are used in cosmetics, pharmaceuticals, and lubricants as well as a potential biofuel. Plasmid vectors are used to drive … [Read more...] about Plasmid Library for Fatty Alcohol Production by Cupriavidus Necator 2022-028