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Intellectual Property Office

Biotech Software

Multi-Omics Data Library for Predictive Modeling  2021-007

APPLICATIONS: Predictive modeling for bioengineering and synthetic biology  BENEFITS: Enables accurate testing of biological computational and algorithmic tools  Provides reliable synthetic biological data  BACKGROUND: Synthetic biology cannot yet fulfill its potential due to the inability to predict the behavior of biological systems. Computational tools … [Read more...] about Multi-Omics Data Library for Predictive Modeling  2021-007

Joint Genome Institute Analysis Workflow Service (JAWS) for Complex Computational Pipelines on Multiple Compute Resources 2020-090

APPLICATIONS: Running large, complex computational workflows, pipelines (e.g., Broad Institute’s Cromwell) Data analysis workflows in High Performance Computing (HPC), large cluster, and cloud environments  BENEFITS: Improves reusability and robustness of workflows/pipelines  Allows for easier maintenance and modification Enables distribution of workflows … [Read more...] about Joint Genome Institute Analysis Workflow Service (JAWS) for Complex Computational Pipelines on Multiple Compute Resources 2020-090

DelPlasmid: Finding Plasmids with Deep Learning and Machine Learning 2019-037

APPLICATIONS OF TECHNOLOGY: Identification of plasmids in assembled bacterial genomes BENEFITS: Recovery of plasmids from assembled bacterial genomes without any prior taxonomical knowledge with a low false positive rate  BACKGROUND: Plasmids are extrachromosomal genetic elements that are an important driver of DNA exchange and genetic innovation in … [Read more...] about DelPlasmid: Finding Plasmids with Deep Learning and Machine Learning 2019-037

ClusterCAD: Computational Platform for Design of Chimeric Polyketide Synthase (PKS) enzymes 2017-101

APPLICATIONS OF TECHNOLOGY:  Drug development Bioproducts Chemical Engineering BENEFITS:  Saves time in developing novel or drop-in molecules using type I PKS Easily identify polyketide synthase (PKS) modules based either on amino acid sequence or on the chemical structure of the cognate polyketide intermediate More reliable construction of functional … [Read more...] about ClusterCAD: Computational Platform for Design of Chimeric Polyketide Synthase (PKS) enzymes 2017-101