APPLICATIONS OF TECHNOLOGY: Reduces complexity of genome Differentiates similar regions from mixed genomes, i.e., mixed cancer and normal cells from cancer tissue Enables haplotype genome sequencing Enables complex genome and metagenome assembly ADVANTAGES: Sequences and assembles a large number of long single DNA molecules without indexing during … [Read more...] about Long-range Barcode Labeled Sequencing for Efficient Genome and Metagenome Assembly IB-3019
Synthetic Biology Tools and Software
Multinozzle Emitter Array (MEA) for On-chip Mass Spectrometry IB-2977
APPLICATIONS OF TECHNOLOGY: In vitro diagnostics Biopharmaceutical R&D Systems biology laboratory research Single-cell “omics” Lab-on-a-chip analyses Food safety testing Environmental monitoring ADVANTAGES: Robust and scalable silicon fabrication technologies High-throughput multiplexing, i.e., processing multiple analytes sequentially … [Read more...] about Multinozzle Emitter Array (MEA) for On-chip Mass Spectrometry IB-2977
Cell Surface Modification for Single Cell Analysis, Biosensing, and Tissue Engineering JIB-2703
APPLICATIONS OF TECHNOLOGY: Screening platforms for pharmaceuticals Biological production of biofuels Tissue engineering Cell-based biosensing ADVANTAGES: Faster and more biocompatible than existing methods Works for virtually all mammalian, plant, bacterial, and fungal cells Minimal to no effect on intracellular signaling pathways Enables … [Read more...] about Cell Surface Modification for Single Cell Analysis, Biosensing, and Tissue Engineering JIB-2703
Library of Plasmids to Control Gene Expression Levels EIB-2792
APPLICATIONS OF TECHNOLOGY: Biofuel production Pharmaceutical and chemical production Biological research involving gene expression ADVANTAGES: Enables control over gene expression Applicable with any genes lacking 4 particular restriction sites ABSTRACT: Taek Soon Lee and colleagues at the Joint BioEnergy Institute (JBEI) have developed a technology that … [Read more...] about Library of Plasmids to Control Gene Expression Levels EIB-2792
Rapid Discovery and Optimization of Enzyme Solutions Using Tagged Biomass and Mass Spectrometry EJIB-3262
APPLICATIONS Biofuel production Glycobiology Drug discovery Enzyme bioengineering ADVANTAGES Allows native substrates to screen for specific enzymatic activities Small sample volume, high throughput Potential to aid explanation of enzyme catalytic mechanism ABSTRACT Creating optimal enzymes to improve the efficiency of converting biomass into sugars … [Read more...] about Rapid Discovery and Optimization of Enzyme Solutions Using Tagged Biomass and Mass Spectrometry EJIB-3262