High Throughput Characterization of Bacterial Promoters From Their Host Environments 2022-081 This invention, dubbed “PiSeq,” characterizes bacterial promoters and can enable identification of biosensors for chemicals and physical conditions associated with their host’s physiology and environment. Inventors: Tomoya Honda, Yasuo Yoshikuni. Contact: Jeremy … [Read more...] about Sequencing and Screening Technologies
Synthetic Biology Tools and Software
High Throughput Characterization of Bacterial Promoters From Their Host Environments 2022-081
APPLICATIONS OF TECHNOLOGY: Health diagnoses (e.g., biomarker analysis) Environmental monitoring (e.g., soil, drinking water) Beauty and health (i.e. living therapeutics for skin conditions) Agriculture Drugs (i.e. search for biosensors associated with diseases) BENEFITS: Uses a DNA-barcoded promoter library and offers a rapid … [Read more...] about High Throughput Characterization of Bacterial Promoters From Their Host Environments 2022-081
Registries of Biological Parts: Inventory of Composable Elements (ICE) and Web of Registries, Bioparts Search Portal 2639
APPLICATIONS OF TECHNOLOGY: Search, storage, and management of databases of biological parts and associated sequences Visualisation of biological part sequences BENEFITS: Efficient sourcing and management of data Facilitates data sharing and exchange TECHNOLOGY OVERVIEW: ICE and Web of Registries The Inventory of Composable Elements (ICE) is an open … [Read more...] about Registries of Biological Parts: Inventory of Composable Elements (ICE) and Web of Registries, Bioparts Search Portal 2639
High-Throughput Protein Pull-Down for Mapping Transcription Factors, “Biotin DAP-seq” 2021-071
APPLICATIONS OF TECHNOLOGY: Translation of DNA sequences into affinity labeled proteins Protein isolation for downstream characterization For application in transcription factor (TF) binding site discovery methods (e.g., DAP-seq, SELEX), RNA protein-binding site discovery, and protein-protein interaction studies BENEFITS: This method is equally effective, … [Read more...] about High-Throughput Protein Pull-Down for Mapping Transcription Factors, “Biotin DAP-seq” 2021-071
DelPlasmid: Finding Plasmids with Deep Learning and Machine Learning 2019-037
APPLICATIONS OF TECHNOLOGY: Identification of plasmids in assembled bacterial genomes BENEFITS: Recovery of plasmids from assembled bacterial genomes without any prior taxonomical knowledge with a low false positive rate BACKGROUND: Plasmids are extrachromosomal genetic elements that are an important driver of DNA exchange and genetic innovation in … [Read more...] about DelPlasmid: Finding Plasmids with Deep Learning and Machine Learning 2019-037