APPLICATIONS OF TECHNOLOGY: Drug discovery and screening Functional genomics Synthetic biology Enzyme discovery ADVANTAGES: High throughput Scalable Less labor intensive and expensive than current approaches Enables gene function annotation ABSTRACT: Though current functional genomics technologies coupled with next generation sequencing have … [Read more...] about Dub-seq: Double Barcoded Shotgun Expression Library Sequencing 2015-160
Synthetic Biology Tools and Software
Toaster Software: Optimizing CRISPR Technologies for Genome Editing 2016-056
APPLICATIONS: Synthetic biology Biotechnology research ADVANTAGES: Design tool for both guide RNA and for CRISPR sequences Models secondary structures ABSTRACT: Researcher Sarah Richardson of the Joint BioEnergy Institute (JBEI) has developed Toaster, a software program that designs Cas9 targeting reagents for non-human model organisms. Given a genome … [Read more...] about Toaster Software: Optimizing CRISPR Technologies for Genome Editing 2016-056
Artificial Metalloproteins For Producing New Chemicals and Materials 2015-184
APPLICATIONS Catalysis for the synthesis of fine chemicals and specialty chemicals Production of new chemicals and materials Stereoselective synthesis, including enantioselective synthesis ADVANTAGES More diverse range of reaction specificity than for small-molecule catalysts Increased speed and selectivity of enzymatic reactions Creation of abiological … [Read more...] about Artificial Metalloproteins For Producing New Chemicals and Materials 2015-184
Strong, Long-Range, Aligned Lamellar Structures for Biomedical (Synthetic Bone) and Energy Applications 2015-018
APPLICATIONS: Synthetic bone scaffolding Water purification filters Fuel cell electrodes Tissue engineering ADVANTAGES: Strong, tough, and lightweight Anisotropic properties that mimic natural materials Appropriate for many composite materials ABSTRACT: Researchers working in Berkeley Lab’s Materials Sciences Division have developed … [Read more...] about Strong, Long-Range, Aligned Lamellar Structures for Biomedical (Synthetic Bone) and Energy Applications 2015-018
Precise, High Throughput Droplet Manipulation 2013-128
APPLICATIONS: Research – pharmaceutical, enzyme, genetics ADVANTAGES: Can screen an extremely large number of biological samples Capable of evaluating multiple experimental conditions at one time Generates droplets quickly and efficiently based on various characteristics Utilizes new and effective droplet mixing and sorting … [Read more...] about Precise, High Throughput Droplet Manipulation 2013-128