APPLICATIONS OF TECHNOLOGY: Genome editing Genetic engineering Gene therapy Research tools (e.g., high-throughput screening of gene functions in cell lines and in vivo) Creation of transgenic animal models ADVANTAGES: Functions under different conditions than current CRISPR-Cas9 proteins (e.g, thermostable and enzymatically active in a wide temperature … [Read more...] about Thermostable RNA-Guided Endonucleases (GEOCAS9) 2017-117
Available Technologies
Enhancing Nitrogen Fertilizer Efficiency 2016-155
APPLICATIONS OF TECHNOLOGY: Agriculture ADVANTAGES: Reduced nitrogen loss to the atmosphere during fertilization More sustainable and economically profitable agricultural practices Improved agricultural efficiency ABSTRACT: Berkeley Lab’s Hans Carlson and Adam Deutschbauer have developed a technology to facilitate microbial nitrate reduction in nitrogen … [Read more...] about Enhancing Nitrogen Fertilizer Efficiency 2016-155
Endoscopic Laser Ablation for Curved / Twisted Tubing 2015-124
APPLICATIONS OF TECHNOLOGY: Ultra-high vacuum Coatings on accelerator components ADVANTAGES: Enables deposition on the inside of tubes 6 mm in diameter, and smaller Enables deposition on the inside of hollow, curved components In-situ coating and activation ABSTRACT: While high-aspect ratio and/or curved tubing is important for improving accelerator … [Read more...] about Endoscopic Laser Ablation for Curved / Twisted Tubing 2015-124
Intelligent System for Personalized Ambient Comfort and Energy Efficiency 2016-183
APPLICATIONS OF TECHNOLOGY: Commercial buildings including offices, hotels, classrooms with multiple occupants with varying comfort needs Residences Vehicles HVAC and lighting controls Intelligent furniture ADVANTAGES: Provides hyperlocal environmental sensing, e.g., ambient temperature, humidity, air quality, daylight, noise Integrates localized … [Read more...] about Intelligent System for Personalized Ambient Comfort and Energy Efficiency 2016-183
Decorporation Agent for Therapeutic Chelation of Industrial and Clinical Toxic Heavy Metals 2016-078
APPLICATIONS OF TECHNOLOGY: Treatment and prevention of gadolinium deposition in patients undergoing MRIs Treatment for exposure to toxic metals including lead, tin, and cadmium ADVANTAGES: Strong decorporation efficacy High affinity for the toxic elements gadolinium (Gd), lead (Pb), tin (Sn), and cadmium (Cd) ABSTRACT: Researchers at Berkeley Lab have … [Read more...] about Decorporation Agent for Therapeutic Chelation of Industrial and Clinical Toxic Heavy Metals 2016-078