An optical microscope for fast, high contrast 2-D and 3-D imaging of structures beneath the surface of large biological samples, such as the cerebral cortex of live mammal brains. Compatible with conventional wide-field microscopes, the Berkeley Lab technology offers a ready way to improve the imaging capabilities of conventional optical microscopes. APPLICATIONS OF … [Read more...] about Axial and Arbitrary Plane Optical Microscope 2013-153
Physical Sciences
Optofluidics for Sensing Single Particles IB- 2013-084
APPLICATIONS OF TECHNOLOGY: Imaging for Medical diagnostics Point-of-care applications Environmental monitoring Forensics ADVANTAGES: Ultra high sensitivity and spatial resolution with real time detection Works for very high and very low concentrations Can simultaneously confine light and liquid to sub-50nm regions Doesn’t require highly trained … [Read more...] about Optofluidics for Sensing Single Particles IB- 2013-084
Atomic-Resolution Transmission Electron Microscope Cell for Use with Liquid Samples 2013-011
APPLICATIONS OF TECHNOLOGY: Transmission Electron Microscopy for manufacturing and research ADVANTAGES: Reactions can be observed at atomic resolution Versatile micro/nanofluidic setup can be used to study either biological samples or nanomaterials in liquids Ability to mix two or more solutions and observe changes at atomic resolution Can be mass … [Read more...] about Atomic-Resolution Transmission Electron Microscope Cell for Use with Liquid Samples 2013-011
Detection of J-Couplings at Zero Magnetic Field Using Atomic Magnetometers JIB-2664
APPLICATIONS OF TECHNOLOGY: Drug design Catalyst evaluation and optimization Research tool for pharmaceutical and biomedical industries Portable NMR detectors Detection of liquid explosives ADVANTAGES: Does not require superconducting magnets or cryogenics Enables high resolution two-dimensional spectroscopy Accurate representation of bonds forming and … [Read more...] about Detection of J-Couplings at Zero Magnetic Field Using Atomic Magnetometers JIB-2664
Remote Detection of Blood Flow in Living Systems with Background-free MRI IB-2444
APPLICATIONS OF TECHNOLOGY: Clinical and experimental MRI Portable MRI MRI for patients with metal/electronic devices ADVANTAGES: Higher resolution blood flow imaging compared to existing MRI machines Measures regional blood flow parameters, not only local velocities Images have less background noise May be implemented, with minor modifications, in … [Read more...] about Remote Detection of Blood Flow in Living Systems with Background-free MRI IB-2444