APPLICATIONS OF TECHNOLOGY: Biomanufacturing of enzymes Enzyme research ADVANTAGES: Rapid discovery of the function of genes Capable of multiplexing Ultra-high-throughput ABSTRACT: Researchers at Berkeley Lab led by Trent Northen have developed the ARGO (Assignment of the Reactions of Gene products in Organisms) platform, an efficient and scalable … [Read more...] about ARGO: Peptide Barcoding for Genomic Discovery 2015-123
Spectroscopy
Quantitative Differential Electrochemical Mass Spectrometer Cell 2014-102
APPLICATIONS: Mass spectrometry Fuel cell development ADVANTAGES: Enables quantitative real time analysis of gaseous or volatile electrochemical reaction products Rapid response time (~1 s) High product collection efficiency Parallel electrode geometry ensures uniform potential applied across the working electrode surface Ion-conducting membrane separates … [Read more...] about Quantitative Differential Electrochemical Mass Spectrometer Cell 2014-102
AIRLAB-MS for Analysis of Complex Biological Systems Under Native Conditions 2014-084
APPLICATIONS OF TECHNOLOGY: Biofuel development Research – pharmaceutical, medical, agricultural ADVANTAGES: Samples biological systems under native conditions with no preparation Integrates laser ablation sampling and mass spectrometry with IR microscopy High transfer efficiency of ~50% Spatially resolved chemical composition ABSTRACT: Berkeley … [Read more...] about AIRLAB-MS for Analysis of Complex Biological Systems Under Native Conditions 2014-084
Small, Photostable, Non-blinking Upconverting Nanocrystals for Imaging IB-3130
APPLICATIONS OF TECHNOLOGY: Luminescent tags for biological imaging – single molecule to whole animal High-throughput screening for drug discovery Nanocrystal lasers Photovoltaics Digital displays LEDs Infrared and chemical sensors Optoelectronic communications ADVANTAGES: Efficiently upconverts infrared to visible light Responds to … [Read more...] about Small, Photostable, Non-blinking Upconverting Nanocrystals for Imaging IB-3130
Nanostructure Initiator Mass Spectrometry (NIMS) Flux Imaging JIB-3066
APPLICATIONS OF TECHNOLOGY: Medical diagnostics and therapeutic classification Biotechnology research and development Developmental biology ADVANTAGES: Enables metabolic flux imaging, not possible by other techniques Overcomes quantification challenges in mass spectrometry imaging ABSTRACT: Using time dependent isotopic labeling and mass spectrometry … [Read more...] about Nanostructure Initiator Mass Spectrometry (NIMS) Flux Imaging JIB-3066