APPLICATIONS OF TECHNOLOGY: Biomechanics Cancer research Polymer chemistry Optomechanical devices Failure analysis ADVANTAGES: Nanonewton sensitivity Nanoscale spatial resolution Fluorescent signal ABSTRACT: A team of Berkeley Lab scientists led by Paul Alivisatos and Charina Choi has developed a nanoscale stress sensor made of spider-like, … [Read more...] about Luminescent Nanocrystal Stress Gauge JIB-2727
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Highly Sensitive Detector for Radiotracer Chromatography IB-2765
APPLICATIONS OF TECHNOLOGY: Analytical radiotracer high performance liquid chromatography (HPLC) Research of metabolic pathways for biofuels, drug development and medical diagnostics ADVANTAGES: One hundred times more sensitive than existing radiotracer HPLC Can be manufactured with existing hardware ABSTRACT: Scientists at Berkeley Lab have developed an … [Read more...] about Highly Sensitive Detector for Radiotracer Chromatography IB-2765
High Throughput Purification and Identification of Cellular Protein Complexes JIB-2538
APPLICATIONS OF TECHNOLOGY: Biomedical research, drug design Biofuels Biodecontamination ADVANTAGES: More efficient than target affinity purification May be scaled up for high throughput Identifies multiple protein complexes simultaneously Low false positive and false negative rates ABSTRACT: Scientists at Berkeley Laboratory and the University of … [Read more...] about High Throughput Purification and Identification of Cellular Protein Complexes JIB-2538
Cell Characterization by Phenotypic Analysis of Ligand Redistribution IB-2640
APPLICATIONS OF TECHNOLOGY: Drug design and testing Diagnosis and treatment of cancer and other diseases ADVANTAGES: Can be applied to living cells from biopsies Compatible with samples as small as a single cell May be scaled up to test multiple drugs simultaneously Analyzes phenotype rather than gene or protein expression Mimics and assesses … [Read more...] about Cell Characterization by Phenotypic Analysis of Ligand Redistribution IB-2640
A Cell Injection System Using Carbon Nanotubes IB-2323, IB-2333
APPLICATIONS OF TECHNOLOGY: Transfection of foreign molecular-scale cargoes into cells (e.g. DNA, RNA, polymers, dendrimers, nanoparticles, etc.) Insertion of probes into cells to observe physical and biochemical interactions. (e.g. quantum dots-probes) ADVANTAGES: Unlike microinjection, nanoneedle injection does not damage the cell membrane Overcomes other … [Read more...] about A Cell Injection System Using Carbon Nanotubes IB-2323, IB-2333