APPLICATIONS OF TECHNOLOGY: Purification of five different His-tagged proteins expressed in E. coli using the Berkeley Lab His-tag aptamer magnetic beads (1a-5a) or commercially available … [Read more...] about Aptamer for the Histidine Tag and an Improved Method for the Generation of High Affinity Aptamers IB-1929
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Optimum Protein Solubility Screen IB-2005
APPLICATIONS OF TECHNOLOGY: Protein preparation for x-ray crystallography and NMR Protein purification kits and reagents Protein functional analysis ADVANTAGES: Rapidly identifies optimal conditions for protein solubility Works with very small amounts of protein (240 mg) Readily adaptable for high throughput processing; easily scalable to larger … [Read more...] about Optimum Protein Solubility Screen IB-2005
Biomarker for Cell Senescence IB-1036
E.O. Lawrence Berkeley National Laboratory APPLICATIONS OF TECHNOLOGY: Screen compounds for effects on cell senescence, including high throughput applications Pre and post surgical tissue assay Cancer and aging research ADVANTAGES: This method provides a rapid, convenient and inexpensive basis to: Screen biological or pharmaceutical compounds that have … [Read more...] about Biomarker for Cell Senescence IB-1036
Human Blood Molecular Biodosimeter Panel for Distinguishing Radiation Exposure from Inflammation Stress IB-3304
APPLICATIONS OF TECHNOLOGY: Radiation oncology Medical triage Rapid response in cases of population exposure to ionizing radiation ADVANTAGES: Can be used in a small, handheld device Faster results Higher precision ABSTRACT: Berkeley Lab researchers Andrew Wyrobek and Antoine Snijders have identified a panel of gene and protein biomarkers that will help … [Read more...] about Human Blood Molecular Biodosimeter Panel for Distinguishing Radiation Exposure from Inflammation Stress IB-3304
Mass Spec Testing of Microparticle Lipids for Cancer Diagnosis and Sub-typing IB-3306
APPLICATIONS OF TECHNOLOGY: Cancer diagnosis / prognosis Tumor analysis Identification of invasive sub-types Cancer remission monitoring Disease diagnostics ADVANTAGES: Analyzes microparticle lipids from blood, serum, or tissues Discriminates high growth from low growth cancers Low- to non-invasive diagnostic screening test Rapid – amenable to high … [Read more...] about Mass Spec Testing of Microparticle Lipids for Cancer Diagnosis and Sub-typing IB-3306