APPLICATIONS OF TECHNOLOGY: Personalize therapy using platinum-based anticancer drugs ADVANTAGES: Can be used to tailor cancer treatments to individual patients Reduces unnecessary cancer treatments and the associated side effects Enables new therapeutic strategies for cancer ABSTRACT: Platinum-based anticancer drugs, such as the US approved drugs … [Read more...] about A Diagnostic Test to Personalize Therapy Using Platinum-based Anticancer Drugs JIB-2441
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Methods and Proteins for Developing New Classes of Antibiotics IB-2346
APPLICATIONS OF TECHNOLOGY: Antibiotics for human and veterinary medicine Pesticides for crop management Food preservatives Genes engineered into probiotic bacteria ADVANTAGES: Overcomes antibiotic-resistance of bacteria Isolates new types of antimicrobial proteins that can be used for: Topical applications (ointment, cream, or lotion) that prevent … [Read more...] about Methods and Proteins for Developing New Classes of Antibiotics IB-2346
Protease-based Cancer Screening Using Nanoliter Samples IB-2240
APPLICATIONS OF TECHNOLOGY: Early stage screening of cancers via detection of proteases and proteolytic activity in fluid or biopsy samples Prostate cancer detection, and possibly the detection of other protease-related cancers such as breast, colon, kidney, skin, stomach, ovary, and lung cancer ADVANTAGES: Nanoliter sample volumes Reduces false positives for … [Read more...] about Protease-based Cancer Screening Using Nanoliter Samples IB-2240
At-Home Test Kit and Lab Analysis for DNA Damage Assessment 2014-044
An at-home blood collection kit that immediately fixes blood cells’ biological activity enabling non-toxic sample shipment or storage without changes in specific DNA markers. Samples are treated and assessed in an automated, high-throughput, reproducible process yielding results that take each patient’s age, health status and exposure history into account. APPLICATIONS DNA … [Read more...] about At-Home Test Kit and Lab Analysis for DNA Damage Assessment 2014-044
Efficient, Reproducible Immortalization of Normal Human Mammary Epithelial Cells (HMECs) Using Pathologically Relevant Agents JIB- 2013-168
APPLICATIONS OF TECHNOLOGY: Testing potential therapeutics to prevent cancer progression to immortality and malignancy reverse immortalization in cancer cells Assays to identify agents that promote immortalization and malignancy Generation of immortal and malignant lines from any individual’s normal HMEC ADVANTAGES: Unique technology using … [Read more...] about Efficient, Reproducible Immortalization of Normal Human Mammary Epithelial Cells (HMECs) Using Pathologically Relevant Agents JIB- 2013-168