APPLICATIONS OF TECHNOLOGY: Protein preparation for x-ray crystallography and NMR Protein purification kits and reagents Protein functional analysis ADVANTAGES: Rapidly identifies optimal conditions for protein solubility Works with very small amounts of protein (240 mg) Readily adaptable for high throughput processing; easily scalable to larger … [Read more...] about Optimum Protein Solubility Screen IB-2005
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Biomarker for Cell Senescence IB-1036
E.O. Lawrence Berkeley National Laboratory APPLICATIONS OF TECHNOLOGY: Screen compounds for effects on cell senescence, including high throughput applications Pre and post surgical tissue assay Cancer and aging research ADVANTAGES: This method provides a rapid, convenient and inexpensive basis to: Screen biological or pharmaceutical compounds that have … [Read more...] about Biomarker for Cell Senescence IB-1036
Human Blood Molecular Biodosimeter Panel for Distinguishing Radiation Exposure from Inflammation Stress IB-3304
APPLICATIONS OF TECHNOLOGY: Radiation oncology Medical triage Rapid response in cases of population exposure to ionizing radiation ADVANTAGES: Can be used in a small, handheld device Faster results Higher precision ABSTRACT: Berkeley Lab researchers Andrew Wyrobek and Antoine Snijders have identified a panel of gene and protein biomarkers that will help … [Read more...] about Human Blood Molecular Biodosimeter Panel for Distinguishing Radiation Exposure from Inflammation Stress IB-3304
Mass Spec Testing of Microparticle Lipids for Cancer Diagnosis and Sub-typing IB-3306
APPLICATIONS OF TECHNOLOGY: Cancer diagnosis / prognosis Tumor analysis Identification of invasive sub-types Cancer remission monitoring Disease diagnostics ADVANTAGES: Analyzes microparticle lipids from blood, serum, or tissues Discriminates high growth from low growth cancers Low- to non-invasive diagnostic screening test Rapid – amenable to high … [Read more...] about Mass Spec Testing of Microparticle Lipids for Cancer Diagnosis and Sub-typing IB-3306
Genetically Encoded Sensors for Imaging Proteins and Their Complexes IB-3259
APPLICATIONS OF TECHNOLOGY: Fluorescent protein labeling for Medical diagnostics Drug screening Biology research ADVANTAGES: Smaller size than green fluorescent protein (GFP) Long fluorescence lifetime Extends convenient tagging and fluorescence anisotropy (FA) study for larger sized proteins Can be used for FA-imaging of target proteins in living … [Read more...] about Genetically Encoded Sensors for Imaging Proteins and Their Complexes IB-3259