APPLICATIONS OF TECHNOLOGY: High-throughput screening for therapeutics that synergize with TIN2 complex disruption Sensitizing cancer cells to other therapeutic agents Therapy for multiple types of cancer exhibiting p53-negative cancer cells ADVANTAGES: Targets a subset of aggressive cancer cells by using TIN2-complex binding peptides Could be combined … [Read more...] about High Selectivity Peptides for Cancer Therapy, Screening for Cancer Therapies, and Therapy Sensitization IB-2489
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ANXA9: A Therapeutic Target and Predictive Marker for Early Detection of Aggressive Breast Cancer JIB-2371
APPLICATIONS OF TECHNOLOGY: Breast cancer diagnosis Treatment of aggressive breast cancer and cancer resistant to chemotherapy ADVANTAGES: Prevents aggressive breast cancers from metastasizing Offers early detection of aggressive breast cancers May increase survival rates of breast cancer patients May improve response to chemotherapy … [Read more...] about ANXA9: A Therapeutic Target and Predictive Marker for Early Detection of Aggressive Breast Cancer JIB-2371
A Diagnostic Test to Personalize Therapy Using Platinum-based Anticancer Drugs JIB-2441
APPLICATIONS OF TECHNOLOGY: Personalize therapy using platinum-based anticancer drugs ADVANTAGES: Can be used to tailor cancer treatments to individual patients Reduces unnecessary cancer treatments and the associated side effects Enables new therapeutic strategies for cancer ABSTRACT: Platinum-based anticancer drugs, such as the US approved drugs … [Read more...] about A Diagnostic Test to Personalize Therapy Using Platinum-based Anticancer Drugs JIB-2441
Methods and Proteins for Developing New Classes of Antibiotics IB-2346
APPLICATIONS OF TECHNOLOGY: Antibiotics for human and veterinary medicine Pesticides for crop management Food preservatives Genes engineered into probiotic bacteria ADVANTAGES: Overcomes antibiotic-resistance of bacteria Isolates new types of antimicrobial proteins that can be used for: Topical applications (ointment, cream, or lotion) that prevent … [Read more...] about Methods and Proteins for Developing New Classes of Antibiotics IB-2346
Protease-based Cancer Screening Using Nanoliter Samples IB-2240
APPLICATIONS OF TECHNOLOGY: Early stage screening of cancers via detection of proteases and proteolytic activity in fluid or biopsy samples Prostate cancer detection, and possibly the detection of other protease-related cancers such as breast, colon, kidney, skin, stomach, ovary, and lung cancer ADVANTAGES: Nanoliter sample volumes Reduces false positives for … [Read more...] about Protease-based Cancer Screening Using Nanoliter Samples IB-2240