APPLICATIONS OF TECHNOLOGY: Targeted delivery of protein and DNA-based therapeutics Vaccine delivery Cancer immunotherapy Site-specific treatment of inflammation Anti-sense therapy ADVANTAGES: Delivers therapeutic material directly to the cytoplasm of cells Enhances immune response by facilitating cell surface antigen presentation Enables targeted … [Read more...] about Microgels with Acid-Degradable Cross-Linkers for Vaccine and Cytoplasmic Drug Delivery IB-1809a
Cancer Therapeutics
Antibodies for Monitoring and Phosphorylation Sites for Inhibiting DNA Double-Strand Break Repair IB-1807
APPLICATIONS OF TECHNOLOGY: Developing therapeutics for the radiosensitization of cancer cells Assessing the efficacy of cancer treatments Cancer drug screening and development Research on the in vivo activity of DNA-PK ADVANTAGES: Identifies two major DNA-PKcs autophosphorylation sites which are involved in DNA double strand break repair First technology to … [Read more...] about Antibodies for Monitoring and Phosphorylation Sites for Inhibiting DNA Double-Strand Break Repair IB-1807
Quantum Dot Based Cell Motility, Invasion, and Metastasis Assays IB-1755
APPLICATIONS OF TECHNOLOGY: Rapid method for assaying metastatic potential in biopsies Cancer drug development Research on cell motility ADVANTAGES: More photochemically robust than organic dyes Less labor intensive than the Boyden Chamber invasion assay Can be used with live cells no fixation/processing required Allows for real time variation of external … [Read more...] about Quantum Dot Based Cell Motility, Invasion, and Metastasis Assays IB-1755
Synthetic Peptide that Causes Bundling of F-Actin in Vitro and in Situ IB-1571
APPLICATION OF TECHNOLOGY: Pharmaceutical to block cell division of rapidly growing cancer cells Pharmaceutical to block rapid spread of certain highly pathogenic bacteria and viruses Pharmaceutical to prevent metastasis Basic research tool to study the role of the actin cytoskeleton in various in vivo and in vitro processes ADVANTAGES: Synthetic … [Read more...] about Synthetic Peptide that Causes Bundling of F-Actin in Vitro and in Situ IB-1571