APPLICATION OF TECHNOLOGY: Biomass deconstruction BENEFIT: Useful for increasing expression of heterologous proteins in A. niger for: 1) Enzymes compatible with ionic liquids (ILs) for one-pot systems and/or 2) Expression of any heterologous protein BACKGROUND: Efficient and economical deconstruction of biomass is critical for the success of lignocellulosic … [Read more...] about Identification of Gene Targets for Improved Heterologous Enzyme Production in Aspergillus Niger 2017-118
Magnetically Recoverable ZIF Catalysts for the Efficient Depolymerization of Polyesters 2018-055
APPLICATION OF TECHNOLOGY: Post-consumer polyester depolymerization in the presence of diol BENEFITS: Enables facile recovery of the catalyst from the glycolysis products; as a result, the catalyst can be reused without appreciable loss of activity Catalyst shows a broad applicability to various polyester polymer depolymerization Easily prepared by … [Read more...] about Magnetically Recoverable ZIF Catalysts for the Efficient Depolymerization of Polyesters 2018-055
High-Throughput Protein Pull-Down for Mapping Transcription Factors, “Biotin DAP-seq” 2021-071
APPLICATIONS OF TECHNOLOGY: Translation of DNA sequences into affinity labeled proteins Protein isolation for downstream characterization For application in transcription factor (TF) binding site discovery methods (e.g., DAP-seq, SELEX), RNA protein-binding site discovery, and protein-protein interaction studies BENEFITS: This method is equally effective, … [Read more...] about High-Throughput Protein Pull-Down for Mapping Transcription Factors, “Biotin DAP-seq” 2021-071
basecRAWller: Nanopore Sequencing Base Calling Software 2017-075
APPLICATIONS: Nanopore sequencing (i.e. significantly more accurate base caller for nanopore data) BENEFITS: Streaming base calling Base calling from information-rich raw signal BACKGROUND: Nanopore applications require base calling. Current nanopore base calling software applications employ the Viterbi algorithm, which requires the whole sequence to … [Read more...] about basecRAWller: Nanopore Sequencing Base Calling Software 2017-075
DIVA: DNA Design, Implementation, and Validation Automation Software 2021-102
APPLICATIONS: DNA design, DNA construction, synthetic biology, engineering biology, efficiency metric tracking BENEFITS: Provides a collaborative web-based graphical user interface supporting and tracking DNA design and construction. Interfaces with other related enabling software to offer additional functionality and reduce friction for the … [Read more...] about DIVA: DNA Design, Implementation, and Validation Automation Software 2021-102