APPLICATIONS OF TECHNOLOGY: Development of radiopharmaceuticals for cancer diagnosis and treatment Development of antibodies labeled with radionuclides BENEFITS: Simplified synthesis compared to other structures Faster radiolabeling at room temperature Formation of highly stable radiometal complexes Higher synthetic yields BACKGROUND: Thorium-227 … [Read more...] about Chelating Ligands for Enhanced Radiolabeling and Therapeutic Potential 2023-119
Biotechnology
Production of Indigoidine from Metabolically Engineered Pseudomonas putida 2023-064
APPLICATIONS OF TECHNOLOGY: Production of sustainable blue dyes and colorings from renewable lignin carbon streams ADVANTAGES: Reached 77% of maximum theoretical yield of indigoidine from para-coumarate and 7.3 g/L. Does not require that cells enter stationary phase before product can accumulate BACKGROUND: Production of synthetic dyes in the textile … [Read more...] about Production of Indigoidine from Metabolically Engineered Pseudomonas putida 2023-064
Metabolically Engineered Pseudomonas putida for the Bioproduction of Shinorine, a Natural Sunscreen 2021-119
APPLICATIONS OF TECHNOLOGY: Sunscreen cream ADVANTAGES: Environmentally-friendly sunscreen compound High product titer and yield Fast-growing microbe host Eliminates the use of agricultural plants as feedstocks for Shinorine production BACKGROUND: Compounds such as Oxybenzone, Zinc Oxide (ZnO), and Titanium Dioxide, (TiO2) are ubiquitous in many … [Read more...] about Metabolically Engineered Pseudomonas putida for the Bioproduction of Shinorine, a Natural Sunscreen 2021-119
Materials Technologies
Strong, Long-Range, Aligned Lamellar Structures for Biomedical (Synthetic Bone) and Energy Applications 2015-018 This invention addresses traditional freeze casting issues by creating a second temperature gradient to align the freeze fronts and produce lamellar sheets with long-range orientation. Applications include a wide range of composite materials such as Synthetic … [Read more...] about Materials Technologies
Imaging and Analysis Technologies
Novel Fluidic System for Accurate High Speed Atomic Force Microscopy (AFM) and Confocal/Super Resolution Systems 2021-020 This invention provides improved timing and concentration precision compared to current fluidic exchange designs. This tool is ideal for those conducting microscopy-based studies of reaction kinetics. Inventor: Paul Ashby. Contact: Sebastian Ainslie, … [Read more...] about Imaging and Analysis Technologies