APPLICATIONS OF TECHNOLOGY: Production of novel, unnatural bio-active molecules ADVANTAGES: Enables the uptake of artificial cofactor by a host cell and thereby the production of unnatural bio-actives TECHNOLOGY OVERVIEW: Numerous complex biomolecules have been produced by natural or engineered organisms, however, the structures that can be afforded are still … [Read more...] about Host cells and methods for producing unnatural terpenoids using a novel artificial metalloenzyme 2020-049
Bio-based products
Novel Enzymatic Process for the Production of Hydrogen Peroxide 2019-107
APPLICATIONS OF TECHNOLOGY: Paper and pulp industry Production of sodium percarbonate and sodium perborate for laundry detergent Production of propylene oxide Waste water treatment industry ADVANTAGES: Requires less capital-intensive equipment Cost competitive at scale ABSTRACT: Hydrogen peroxide is a commodity chemical produced at 4.5 billion … [Read more...] about Novel Enzymatic Process for the Production of Hydrogen Peroxide 2019-107
Efficient Production of Oxidized Terpenes Via Enzyme Fusion Strategy 2019-108
APPLICATIONS OF TECHNOLOGY: Production of oxidized terpenes and of terpene-based bioproducts (e.g. fuel additives, fragrances, insecticides, pharmaceuticals) BENEFITS: Enables more efficient production of functionalized terpenes BACKGROUND: The functionalization of terpene hydrocarbons using cytochrome P450 enzymes could derive many useful compounds that … [Read more...] about Efficient Production of Oxidized Terpenes Via Enzyme Fusion Strategy 2019-108
High Production Titers and Rates of Tetramethyl Pyrazine 2018-101
APPLICATIONS OF TECHNOLOGY: Food (coffee) flavoring Polymer/ resin component ADVANTAGES: While Corynebacterium glutamicum has been previously reported to produce alkyl pyrazines in mixture at low levels over a long cultivation period, the high production titers and rates of enriched tetramethyl pyrazine in glutamicum in … [Read more...] about High Production Titers and Rates of Tetramethyl Pyrazine 2018-101
A CRISPR-Based and Metabolic Modeling Guided Strategy to Maximizing Indigoidine Production 2019-145
APPLICATIONS OF TECHNOLOGY: Dye and pigment (food, clothing, consumer goods) BACKGROUND: Indigodine is a natural blue pigment that retains its brightness and has direct uses in the dye and pigment industry. Notably, it shows promise as an alternative to synthetic dyes and in providing health benefits as an antioxidant … [Read more...] about A CRISPR-Based and Metabolic Modeling Guided Strategy to Maximizing Indigoidine Production 2019-145