APPLICATIONS OF TECHNOLOGY: Genetic modification of Saccharomyces cerevisiae for pentose fermentation andĀ glucose-fructose isomerization Improved lignocellulose hydrolysate fermentation BENEFITS: Relative to current enzymes, this novel xylose isomerase shows: More than 2.5 times higher specific activity Almost 40% lower Km for D-xylose Higher activity … [Read more...] about A Novel D-Xylose Isomerase for Efficient Lignocellulosic Hydrolysate Fermentation 2019-132
Bio-based products
Host cells and methods for producing unnatural terpenoids using a novel artificial metalloenzyme 2020-049
APPLICATIONS OF TECHNOLOGY: Production of novel, unnatural bio-active molecules ADVANTAGES: Enables the uptake of artificial cofactor by a host cell and thereby the production of unnatural bio-actives TECHNOLOGY OVERVIEW: Numerous complex biomolecules have been produced by natural or engineered organisms, however, the structures that can be afforded are still … [Read more...] about Host cells and methods for producing unnatural terpenoids using a novel artificial metalloenzyme 2020-049
Novel Enzymatic Process for the Production of Hydrogen Peroxide 2019-107
APPLICATIONS OF TECHNOLOGY: Paper and pulp industry Production of sodium percarbonate and sodium perborate for laundry detergent Production of propylene oxide Waste water treatment industry ADVANTAGES: Requires less capital-intensive equipment Cost competitive at scale ABSTRACT: Hydrogen peroxide is a commodity chemical produced at 4.5 billion … [Read more...] about Novel Enzymatic Process for the Production of Hydrogen Peroxide 2019-107
Efficient Production of Oxidized Terpenes Via Enzyme Fusion Strategy 2019-108
APPLICATIONS OF TECHNOLOGY: Production of oxidized terpenes and of terpene-based bioproducts (e.g. fuel additives, fragrances, insecticides, pharmaceuticals) BENEFITS: Enables more efficient production of functionalized terpenes BACKGROUND: The functionalization of terpene hydrocarbons using cytochrome P450 enzymes could derive many useful compounds that … [Read more...] about Efficient Production of Oxidized Terpenes Via Enzyme Fusion Strategy 2019-108
High Production Titers and Rates of Tetramethyl Pyrazine 2018-101
APPLICATIONS OF TECHNOLOGY: Food (coffee) flavoring Polymer/ resin component ADVANTAGES: While Corynebacterium glutamicum has been previously reported to produce alkyl pyrazines in mixture at low levels over a long cultivation period, the high production titers and rates of enriched tetramethyl pyrazine in glutamicum in … [Read more...] about High Production Titers and Rates of Tetramethyl Pyrazine 2018-101