APPLICATIONS OF TECHNOLOGY: Identifying clinically significant subtypes for different tumors BENEFITS: Provides new knowledge that improves diagnosis and optimization of treatment Cost-effective compared with hematoxylin and eosin (H&E) stained histology sections Promises significant clinical value combined with well-known factors (i.e., clinical factors … [Read more...] about Discovery of Robust Cellular Morphometric Subtypes in Lower Grade Glioma through Machine Learning 2021-064
Human Health/Precision Medicine
Tomographic Electrical Rhizosphere Imager (TERI) for Efficient Quantification of Plant Root Traits 2020-001
APPLICATIONS OF TECHNOLOGY: Plant breeding Subsurface plant health and forestry tree health Crop and drought management BENEFITS: Enables quick quantification of underground root parameters in real time Permits imaging of subsurface root structure without disrupting roots BACKGROUND: The development and testing of new chemicals, … [Read more...] about Tomographic Electrical Rhizosphere Imager (TERI) for Efficient Quantification of Plant Root Traits 2020-001
Novel Methods for the Barcoding of Bacteriophages 2019-113
APPLICATIONS OF TECHNOLOGY: Phage engineering Cataloging and Control of phages Diagnosis and Antibiotic Discovery ADVANTAGES: No interference of the phage infection cycle No compromise of the host bacteria life cycle Enables easy amplification of the DNA “barcode” for identification, tracking and control of individual phages Standardizes the workflow … [Read more...] about Novel Methods for the Barcoding of Bacteriophages 2019-113
Synthesis of Gold Nanoparticles Functionalized with 3,4,3-LI(1,2-HOPO) Chelator for Metal Sensing 2020-033
APPLICATIONS OF TECHNOLOGY: Detection of toxic lanthanide and actinides in environmental and waste samples Detection and quantification of f-block elements used as contrast agents in biomedicine ADVANTAGES: High affinity and specificity with f-block elements Single step method The only synthetic protocol to obtain gold nanoparticles functionalized with … [Read more...] about Synthesis of Gold Nanoparticles Functionalized with 3,4,3-LI(1,2-HOPO) Chelator for Metal Sensing 2020-033
Gut Microbiome Engineering for the Heterologous Production of Antiviral Compounds 2019-085
APPLICATIONS OF TECHNOLOGY: Medical: Pharmaceuticals ADVANTAGES: Present strain is among the most robust constituents of the gut microbiome Obviates the need for exogenous iron-sulfur cluster producing genetic elements ABSTRACT: In 2018, Gizzi et al. demonstrated that the human gene Viperin can produce antiviral small molecules (ddhCTP) that act as a chain … [Read more...] about Gut Microbiome Engineering for the Heterologous Production of Antiviral Compounds 2019-085