APPLICATIONS OF TECHNOLOGY: Development of radiopharmaceuticals for cancer diagnosis and treatment Development of antibodies labeled with radionuclides BENEFITS: Simplified synthesis compared to other structures Faster radiolabeling at room temperature Formation of highly stable radiometal complexes Higher synthetic yields BACKGROUND: Thorium-227 … [Read more...] about Chelating Ligands for Enhanced Radiolabeling and Therapeutic Potential 2023-119
Diagnostics
High Throughput Characterization of Bacterial Promoters From Their Host Environments 2022-081
APPLICATIONS OF TECHNOLOGY: Health diagnoses (e.g., biomarker analysis) Environmental monitoring (e.g., soil, drinking water) Beauty and health (i.e. living therapeutics for skin conditions) Agriculture Drugs (i.e. search for biosensors associated with diseases) BENEFITS: Uses a DNA-barcoded promoter library and offers a rapid … [Read more...] about High Throughput Characterization of Bacterial Promoters From Their Host Environments 2022-081
Device & Methods for Diagnostic Spectroscopy of Biomaterials and Live Cells in Aqueous Environments 2020-064
APPLICATIONS OF TECHNOLOGY: Can be applied to different imaging systems including far-field spectromicroscopy and near-field nanospectroscopy Examples of suitable applications include: characterization of exosomes, vesicles, viruses, microbe-host cell interactions, enzymatic deconstruction of plant materials, biogeochemical processes, signaling during cell migrations … [Read more...] about Device & Methods for Diagnostic Spectroscopy of Biomaterials and Live Cells in Aqueous Environments 2020-064
Single-Photon-Counting Radiation Detector and Data Transmission Methods 2021-113
APPLICATIONS OF TECHNOLOGY: Radiation detectors Positron emission tomography (PET) systems BENEFITS: High fidelity position, energy, and time information provided Lower cost than silicon photomultipliers Reduced signal processing footprint BACKGROUND: Radiation detectors work by turning incoming radiation into electrical signals, and information … [Read more...] about Single-Photon-Counting Radiation Detector and Data Transmission Methods 2021-113
Discovery of Robust Cellular Morphometric Subtypes in Lower Grade Glioma through Machine Learning 2021-064
APPLICATIONS OF TECHNOLOGY: Identifying clinically significant subtypes for different tumors BENEFITS: Provides new knowledge that improves diagnosis and optimization of treatment Cost-effective compared with hematoxylin and eosin (H&E) stained histology sections Promises significant clinical value combined with well-known factors (i.e., clinical factors … [Read more...] about Discovery of Robust Cellular Morphometric Subtypes in Lower Grade Glioma through Machine Learning 2021-064