APPLICATIONS OF TECHNOLOGY: Development of radiopharmaceuticals for cancer diagnosis and treatment Development of antibodies labeled with radionuclides BENEFITS: Simplified synthesis compared to other structures Faster radiolabeling at room temperature Formation of highly stable radiometal complexes Higher synthetic yields BACKGROUND: Thorium-227 … [Read more...] about Chelating Ligands for Enhanced Radiolabeling and Therapeutic Potential 2023-119
Diagnostics
High Throughput Characterization of Bacterial Promoters From Their Host Environments 2022-081
APPLICATIONS OF TECHNOLOGY: Health diagnoses (e.g., biomarker analysis) Environmental monitoring (e.g., soil, drinking water) Beauty and health (i.e. living therapeutics for skin conditions) Agriculture Drugs (i.e. search for biosensors associated with diseases) BENEFITS: Uses a DNA-barcoded promoter library and offers a rapid … [Read more...] about High Throughput Characterization of Bacterial Promoters From Their Host Environments 2022-081
Device & Methods for Diagnostic Spectroscopy of Biomaterials and Live Cells in Aqueous Environments 2020-064
APPLICATIONS OF TECHNOLOGY: Can be applied to different imaging systems including far-field spectromicroscopy and near-field nanospectroscopy Examples of suitable applications include: characterization of exosomes, vesicles, viruses, microbe-host cell interactions, enzymatic deconstruction of plant materials, biogeochemical processes, signaling during cell migrations … [Read more...] about Device & Methods for Diagnostic Spectroscopy of Biomaterials and Live Cells in Aqueous Environments 2020-064
Single-Photon-Counting Radiation Detector and Data Transmission Methods 2021-113
APPLICATIONS OF TECHNOLOGY: Radiation detectors Positron emission tomography (PET) systems BENEFITS: High fidelity position, energy, and time information provided Lower cost than silicon photomultipliers Reduced signal processing footprint BACKGROUND: Radiation detectors work by turning incoming radiation into electrical signals, and information … [Read more...] about Single-Photon-Counting Radiation Detector and Data Transmission Methods 2021-113
Microbiome Signature for Prognosis of Breast Cancer Patients 2021-175
APPLICATIONS OF TECHNOLOGY: Novel methods for predicting the overall prognosis of breast cancer patients BENEFITS: Integration of microbial abundance prognosis score (MAPS) into the nomogram significantly improves prognosis prediction BACKGROUND: Prognosis of breast cancer patients differs considerably and there is a need for identifying a … [Read more...] about Microbiome Signature for Prognosis of Breast Cancer Patients 2021-175