APPLICATIONS OF TECHNOLOGY: Identifying clinically significant subtypes for different tumors BENEFITS: Provides new knowledge that improves diagnosis and optimization of treatment Cost-effective compared with hematoxylin and eosin (H&E) stained histology sections Promises significant clinical value combined with well-known factors (i.e., clinical factors … [Read more...] about Discovery of Robust Cellular Morphometric Subtypes in Lower Grade Glioma through Machine Learning 2021-064
Diagnostics
Novel Methods for the Barcoding of Bacteriophages 2019-113
APPLICATIONS OF TECHNOLOGY: Phage engineering Cataloging and Control of phages Diagnosis and Antibiotic Discovery ADVANTAGES: No interference of the phage infection cycle No compromise of the host bacteria life cycle Enables easy amplification of the DNA “barcode” for identification, tracking and control of individual phages Standardizes the workflow … [Read more...] about Novel Methods for the Barcoding of Bacteriophages 2019-113
Synthesis of Gold Nanoparticles Functionalized with 3,4,3-LI(1,2-HOPO) Chelator for Metal Sensing 2020-033
APPLICATIONS OF TECHNOLOGY: Detection of toxic lanthanide and actinides in environmental and waste samples Detection and quantification of f-block elements used as contrast agents in biomedicine ADVANTAGES: High affinity and specificity with f-block elements Single step method The only synthetic protocol to obtain gold nanoparticles functionalized with … [Read more...] about Synthesis of Gold Nanoparticles Functionalized with 3,4,3-LI(1,2-HOPO) Chelator for Metal Sensing 2020-033
PUMA: Ultrasensitive Detection of Biological and Chemical Agents 2017-054
APPLICATIONS OF TECHNOLOGY: • Point-of-care clinical diagnostics • Remote sensing of hazardous materials • Toxic gas leak detection • Physical incorporation into cell phones or small devices for remote detection, e.g., drones ADVANTAGES: • High specificity in analyte identification • Small in size for field portability • Low power requirement and cost • … [Read more...] about PUMA: Ultrasensitive Detection of Biological and Chemical Agents 2017-054
Biomarkers for Predicting Lung Cancer Survival 2017-082
APPLICATIONS OF TECHNOLOGY: Lung cancer survival diagnostic product ADVANTAGES: Robustly predicts overall survival of lung adenocarcinoma patients Enables stratification in clinical trials ABSTRACT: Researchers at Lawrence Berkeley National Laboratory have developed a multi-step, bioinformatics strategy to mine large omics and clinical data, building a … [Read more...] about Biomarkers for Predicting Lung Cancer Survival 2017-082