APPLICATIONS OF TECHNOLOGY: Phage engineering Cataloging and Control of phages Diagnosis and Antibiotic Discovery ADVANTAGES: No interference of the phage infection cycle No compromise of the host bacteria life cycle Enables easy amplification of the DNA “barcode” for identification, tracking and control of individual phages Standardizes the workflow … [Read more...] about Novel Methods for the Barcoding of Bacteriophages 2019-113
Diagnostics
Synthesis of Gold Nanoparticles Functionalized with 3,4,3-LI(1,2-HOPO) Chelator for Metal Sensing 2020-033
APPLICATIONS OF TECHNOLOGY: Detection of toxic lanthanide and actinides in environmental and waste samples Detection and quantification of f-block elements used as contrast agents in biomedicine ADVANTAGES: High affinity and specificity with f-block elements Single step method The only synthetic protocol to obtain gold nanoparticles functionalized with … [Read more...] about Synthesis of Gold Nanoparticles Functionalized with 3,4,3-LI(1,2-HOPO) Chelator for Metal Sensing 2020-033
PUMA: Ultrasensitive Detection of Biological and Chemical Agents 2017-054
APPLICATIONS OF TECHNOLOGY: • Point-of-care clinical diagnostics • Remote sensing of hazardous materials • Toxic gas leak detection • Physical incorporation into cell phones or small devices for remote detection, e.g., drones ADVANTAGES: • High specificity in analyte identification • Small in size for field portability • Low power requirement and cost • … [Read more...] about PUMA: Ultrasensitive Detection of Biological and Chemical Agents 2017-054
Spectroscopic Imaging and Analysis of Live Cells 2015-077
ABSTRACT: Researchers at Berkeley Lab led by Hoi-Ying Holman have developed technologies for measurement, visualization, and analysis of chemical dynamics in living cells or tissues for diagnostic pathology. Devices can be open- or closed-channel microfluidic membrane devices for long-term IR spectroscopy of live adherent cells and ultimately for rapidly identifying … [Read more...] about Spectroscopic Imaging and Analysis of Live Cells 2015-077
A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
APPLICATIONS OF TECHNOLOGY: Targeted cancer therapies Prediction of relapse-free survival ADVANTAGES: Determines most effective treatment options for patient quality of life Standardizes breast cancer prognoses ABSTRACT: A Berkeley Lab research team led by Antoine Snijders has identified a 12-gene signature that can be used to predict relapse-free … [Read more...] about A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181