APPLICATIONS OF TECHNOLOGY: Microbiome engineering for medicine, agriculture, biomanufacturing and renewable energy Pharmaceutical synthesis Commodity chemical and biofuel production Livestock research and development ADVANTAGES: Enables high-throughput, stable, accurate, efficient gene integration and expression of very large DNA constructs (e.g., … [Read more...] about A Universal Approach to Integrate and Express Pathways in a Broad Range of Bacteria 2016-024
Human Health/Precision Medicine
Safe Preparation of Black Silicon Substrate for Nanostructure Initiator Mass Spectrometry (NIMS) 2015-122
APPLICATIONS: NIMS platform for analysis of biological molecules ADVANTAGES: More consistent, controlled NIMS chip production Does not require hydrofluoric acid Characteristics of the black silicon can be modified to alter NIMS sensitivity ABSTRACT: Trent Northen and other Berkeley Lab researchers have demonstrated a new technology for preparing black … [Read more...] about Safe Preparation of Black Silicon Substrate for Nanostructure Initiator Mass Spectrometry (NIMS) 2015-122
A Long Non-Coding RNA Expressed in Aggressive Cancer 2014-109
ABSTRACT Berkeley Lab researchers have developed technologies to evaluate levels of the long, non-coding RNA to assess the aggressiveness of a cancer and to modulate levels of the long non-coding RNA. This invention addresses the need to identify patients with potentially metastatic tumors versus non-metastatic tumors. For more details, see Published PCT patent … [Read more...] about A Long Non-Coding RNA Expressed in Aggressive Cancer 2014-109
Selective Modification of Proteins 2015-038
APPLICATIONS: Pharmaceutical therapeutics Biochemical sensors Building blocks for bio-based materials ADVANTAGES: Provides well defined method of modification Site specific Allows for control of the degree of modification ABSTRACT: Researchers at Lawrence Berkeley National Lab and the University of California, Berkeley have developed a technology … [Read more...] about Selective Modification of Proteins 2015-038
Basal Media for Culturing Epithelial Cells 2015-009
APPLICATIONS: Growing primary human epithelial cells for Pharmaceutical development Toxicology Biotechnology research ADVANTAGES: Regular and consistent formulation Superior growth for 1/12 of the price Up to 60 population doublings Can sustain long term cultures ABSTRACT: Researchers at Berkeley Lab have developed a low cost technology for growing … [Read more...] about Basal Media for Culturing Epithelial Cells 2015-009