APPLICATIONS OF TECHNOLOGY: Reduces complexity of genome Differentiates similar regions from mixed genomes, i.e., mixed cancer and normal cells from cancer tissue Enables haplotype genome sequencing Enables complex genome and metagenome assembly ADVANTAGES: Sequences and assembles a large number of long single DNA molecules without indexing during … [Read more...] about Long-range Barcode Labeled Sequencing for Efficient Genome and Metagenome Assembly IB-3019
Human Health/Precision Medicine
High Throughput Nanoparticle Delivery to the Cytosol of Living Cells IB-2849
APPLICATIONS OF TECHNOLOGY: Basic and applied research on intracellular processes Biological imaging Medical diagnostics Pharmaceutical development ADVANTAGES: Rapid cytosolic delivery within a few hours of incubation Mere picomolar concentrations of nanoparticles required for labeling Amenable to most nanoparticle formulations and cell/tissue … [Read more...] about High Throughput Nanoparticle Delivery to the Cytosol of Living Cells IB-2849
Highly Sensitive Detector for Radiotracer Chromatography IB-2765
APPLICATIONS OF TECHNOLOGY: Analytical radiotracer high performance liquid chromatography (HPLC) Research of metabolic pathways for biofuels, drug development and medical diagnostics ADVANTAGES: One hundred times more sensitive than existing radiotracer HPLC Can be manufactured with existing hardware ABSTRACT: Scientists at Berkeley Lab have developed an … [Read more...] about Highly Sensitive Detector for Radiotracer Chromatography IB-2765
Simply Executed Nano-based Membrane Binding Sensor JIB-2649
APPLICATIONS OF TECHNOLOGY: Drug design, screening, and in vivo testing Clinical laboratory assays Biomedical research ADVANTAGES: Inexpensive implementation Can be achieved with a standard bench top spectrophotometer Scales up for high throughput Records real-time binding kinetics High signal-to-noise ratio Label-free detection ABSTRACT: Jay … [Read more...] about Simply Executed Nano-based Membrane Binding Sensor JIB-2649
Cell Surface Modification for Single Cell Analysis, Biosensing, and Tissue Engineering JIB-2703
APPLICATIONS OF TECHNOLOGY: Screening platforms for pharmaceuticals Biological production of biofuels Tissue engineering Cell-based biosensing ADVANTAGES: Faster and more biocompatible than existing methods Works for virtually all mammalian, plant, bacterial, and fungal cells Minimal to no effect on intracellular signaling pathways Enables … [Read more...] about Cell Surface Modification for Single Cell Analysis, Biosensing, and Tissue Engineering JIB-2703