APPLICATIONS OF TECHNOLOGY: Biological and chemical assays Selective metabolite analysis ADVANTAGES: Increased sensitivity to detect targeted metabolites High selectivity to targeted metabolites Extremely sensitive and non-destructive analytical technique ABSTRACT: Nanostructure-initiator Mass Spectrometry (NIMS) is a surface-based mass … [Read more...] about Increased Specificity and Sensitivity to Detect Targeted Metabolites using NIMS 2017-051
Human Health/Precision Medicine
Producing Hydroxytyrosol in Engineered Escherichia Coli 2016-118
APPLICATIONS OF TECHNOLOGY: Dietary supplements Animal feed Antioxidant containing functional food ADVANTAGES: Stable and sustainable formation of antioxidants with high purity Provides a renewable microbial platform for production of a wide range of chemicals ABSTRACT: Joint BioEnergy Institute researchers led by Taek Soon Lee have developed a … [Read more...] about Producing Hydroxytyrosol in Engineered Escherichia Coli 2016-118
ANIcalculator (Average Nucleotide Identity Calculator) 2014-127
APPLICATIONS OF TECHNOLOGY: Genome sequencing ABSTRACT: Increased sequencing of microbial genomes has revealed that prevailing prokaryotic species assignments can be inconsistent with whole genome information for a significant number of species. The long-standing need for a systematic and scalable species assignment technique can be met by the genome-wide Average … [Read more...] about ANIcalculator (Average Nucleotide Identity Calculator) 2014-127
Selective Complexation and Separation of Tetravalent Metal Ions from Other Ions 2017-107
APPLICATIONS OF TECHNOLOGY: Nuclear energy or nuclear fuel reprocessing plants Pharmaceutical isotope production Pharmaceutical companies using lanthanide or actinide drugs Chemical industry ADVANTAGES: Highly selective Improved performance and reliability Versatile process Fewer steps ABSTRACT: Berkeley Lab researchers Rebecca Abergel and … [Read more...] about Selective Complexation and Separation of Tetravalent Metal Ions from Other Ions 2017-107
Thermostable RNA-Guided Endonucleases (GEOCAS9) 2017-117
APPLICATIONS OF TECHNOLOGY: Genome editing Genetic engineering Gene therapy Research tools (e.g., high-throughput screening of gene functions in cell lines and in vivo) Creation of transgenic animal models ADVANTAGES: Functions under different conditions than current CRISPR-Cas9 proteins (e.g, thermostable and enzymatically active in a wide temperature … [Read more...] about Thermostable RNA-Guided Endonucleases (GEOCAS9) 2017-117