APPLICATIONS OF TECHNOLOGY: Nuclear energy or nuclear fuel reprocessing plants Pharmaceutical isotope production Pharmaceutical companies using lanthanide or actinide drugs Chemical industry ADVANTAGES: Highly selective Improved performance and reliability Versatile process Fewer steps ABSTRACT: Berkeley Lab researchers Rebecca Abergel and … [Read more...] about Selective Complexation and Separation of Tetravalent Metal Ions from Other Ions 2017-107
Human Health/Precision Medicine
Thermostable RNA-Guided Endonucleases (GEOCAS9) 2017-117
APPLICATIONS OF TECHNOLOGY: Genome editing Genetic engineering Gene therapy Research tools (e.g., high-throughput screening of gene functions in cell lines and in vivo) Creation of transgenic animal models ADVANTAGES: Functions under different conditions than current CRISPR-Cas9 proteins (e.g, thermostable and enzymatically active in a wide temperature … [Read more...] about Thermostable RNA-Guided Endonucleases (GEOCAS9) 2017-117
A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
APPLICATIONS OF TECHNOLOGY: Targeted cancer therapies Prediction of relapse-free survival ADVANTAGES: Determines most effective treatment options for patient quality of life Standardizes breast cancer prognoses ABSTRACT: A Berkeley Lab research team led by Antoine Snijders has identified a 12-gene signature that can be used to predict relapse-free … [Read more...] about A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
OpenPET Readout Electronics for Radionuclide Imaging 2015-152
APPLICATIONS: Medical imaging Homeland security Other imaging applications ADVANTAGES: High performance - timing resolution, spatial resolution, energy resolution, throughput Supports any kinds of detector and camera configuration Supports virtually any size imager Easily modified via software ABSTRACT: OpenPET is an open source, modular, … [Read more...] about OpenPET Readout Electronics for Radionuclide Imaging 2015-152
ARGO: Peptide Barcoding for Genomic Discovery 2015-123
APPLICATIONS OF TECHNOLOGY: Biomanufacturing of enzymes Enzyme research ADVANTAGES: Rapid discovery of the function of genes Capable of multiplexing Ultra-high-throughput ABSTRACT: Researchers at Berkeley Lab led by Trent Northen have developed the ARGO (Assignment of the Reactions of Gene products in Organisms) platform, an efficient and scalable … [Read more...] about ARGO: Peptide Barcoding for Genomic Discovery 2015-123