APPLICATIONS OF TECHNOLOGY: Treatment of radionuclide exposure Treatment or prevention of gadolinium (Gd) deposition from MRIs Treatment for exposure to toxic metals including lead (Pb), tin (Sn), and cadmium (Cd) ADVANTAGES: Administered orally in a variety of dosage forms Ease of clinical use Enables use during emergencies or mass … [Read more...] about Oral Dosage Forms for Actinide Decorporation Agent 2016-079
Human Health/Precision Medicine
A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
APPLICATIONS OF TECHNOLOGY: Targeted cancer therapies Prediction of relapse-free survival ADVANTAGES: Determines most effective treatment options for patient quality of life Standardizes breast cancer prognoses ABSTRACT: A Berkeley Lab research team led by Antoine Snijders has identified a 12-gene signature that can be used to predict relapse-free … [Read more...] about A Novel 12-Gene Prognostic Signature for Breast Cancer 2016-181
OpenPET Readout Electronics for Radionuclide Imaging 2015-152
APPLICATIONS: Medical imaging Homeland security Other imaging applications ADVANTAGES: High performance - timing resolution, spatial resolution, energy resolution, throughput Supports any kinds of detector and camera configuration Supports virtually any size imager Easily modified via software ABSTRACT: OpenPET is an open source, modular, … [Read more...] about OpenPET Readout Electronics for Radionuclide Imaging 2015-152
ARGO: Peptide Barcoding for Genomic Discovery 2015-123
APPLICATIONS OF TECHNOLOGY: Biomanufacturing of enzymes Enzyme research ADVANTAGES: Rapid discovery of the function of genes Capable of multiplexing Ultra-high-throughput ABSTRACT: Researchers at Berkeley Lab led by Trent Northen have developed the ARGO (Assignment of the Reactions of Gene products in Organisms) platform, an efficient and scalable … [Read more...] about ARGO: Peptide Barcoding for Genomic Discovery 2015-123
Lanthanide-Chelator Barcode for Combinatorial Screening Applications 2016-121
APPLICATIONS OF TECHNOLOGY: Combinatorial screening in Drug discovery and optimization Biomanufacturing Diagnostics ADVANTAGES: Enables faster testing of more diverse conditions / combinations Readily detects lanthanide/chelator complexes Maintains strong lanthanide binding and single-charge ionization Simplified … [Read more...] about Lanthanide-Chelator Barcode for Combinatorial Screening Applications 2016-121