APPLICATIONS OF TECHNOLOGY: Purification of five different His-tagged proteins expressed in E. coli using the Berkeley Lab His-tag aptamer magnetic beads (1a-5a) or commercially available … [Read more...] about Aptamer for the Histidine Tag and an Improved Method for the Generation of High Affinity Aptamers IB-1929
Research
MEA Chips for Integrated Microscopic Imaging and Liquid Chromatography Mass Spectrometry IB-3303
APPLICATIONS OF TECHNOLOGY: In-vitro diagnostics Electrospray ionization mass spectrometry (ESI-MS), chromatography, microscopy, single cell omics, microfluidics Biopharmaceutical R & D Lab-on-a-chip analysis Environmental monitoring ADVANTAGES: Integrated on-chip imaging and liquid chromatography functions Robust and scalable silicon … [Read more...] about MEA Chips for Integrated Microscopic Imaging and Liquid Chromatography Mass Spectrometry IB-3303
Genetically Encoded Sensors for Imaging Proteins and Their Complexes IB-3259
APPLICATIONS OF TECHNOLOGY: Fluorescent protein labeling for Medical diagnostics Drug screening Biology research ADVANTAGES: Smaller size than green fluorescent protein (GFP) Long fluorescence lifetime Extends convenient tagging and fluorescence anisotropy (FA) study for larger sized proteins Can be used for FA-imaging of target proteins in living … [Read more...] about Genetically Encoded Sensors for Imaging Proteins and Their Complexes IB-3259
Increased Glucose Metabolism is Oncogenic; Its Reversal May Be Therapeutic IB-2921
APPLICATIONS OF TECHNOLOGY: Cancer diagnostics Cancer therapeutics Cancer research ADVANTAGES: Provides markers correlated with increased metastases risk Provides for therapies that block or reverse cancer progression through adjusting glucose metabolism ABSTRACT: Berkeley Lab researchers led by Mina Bissell … [Read more...] about Increased Glucose Metabolism is Oncogenic; Its Reversal May Be Therapeutic IB-2921
Quantum Dot Based Cell Motility, Invasion, and Metastasis Assays IB-1755
APPLICATIONS OF TECHNOLOGY: Rapid method for assaying metastatic potential in biopsies Cancer drug development Research on cell motility ADVANTAGES: More photochemically robust than organic dyes Less labor intensive than the Boyden Chamber invasion assay Can be used with live cells no fixation/processing required Allows for real time variation of external … [Read more...] about Quantum Dot Based Cell Motility, Invasion, and Metastasis Assays IB-1755