APPLICATIONS OF TECHNOLOGY: Can be applied to different imaging systems including far-field spectromicroscopy and near-field nanospectroscopy Examples of suitable applications include: characterization of exosomes, vesicles, viruses, microbe-host cell interactions, enzymatic deconstruction of plant materials, biogeochemical processes, signaling during cell migrations … [Read more...] about Device & Methods for Diagnostic Spectroscopy of Biomaterials and Live Cells in Aqueous Environments 2020-064
Research
Separation of Tetravalent Metal Ions using Protein-ligand-based Systems 2016-178
APPLICATIONS OF TECHNOLOGY: Pharmaceutical isotope production Water purification Nuclear waste treatment and portable analysis Production of radiation sources ADVANTAGES: Improved performance and reliability Versatile process Separates different metal ions under soft conditions Scalable and operable at room temperature BACKGROUND: Current … [Read more...] about Separation of Tetravalent Metal Ions using Protein-ligand-based Systems 2016-178
Discovery of Robust Cellular Morphometric Subtypes in Lower Grade Glioma through Machine Learning 2021-064
APPLICATIONS OF TECHNOLOGY: Identifying clinically significant subtypes for different tumors BENEFITS: Provides new knowledge that improves diagnosis and optimization of treatment Cost-effective compared with hematoxylin and eosin (H&E) stained histology sections Promises significant clinical value combined with well-known factors (i.e., clinical factors … [Read more...] about Discovery of Robust Cellular Morphometric Subtypes in Lower Grade Glioma through Machine Learning 2021-064
Novel Methods for the Barcoding of Bacteriophages 2019-113
APPLICATIONS OF TECHNOLOGY: Phage engineering Cataloging and Control of phages Diagnosis and Antibiotic Discovery ADVANTAGES: No interference of the phage infection cycle No compromise of the host bacteria life cycle Enables easy amplification of the DNA “barcode” for identification, tracking and control of individual phages Standardizes the workflow … [Read more...] about Novel Methods for the Barcoding of Bacteriophages 2019-113
Metabolite, Annotation and Gene Integration System (MAGI) and Software 2017-063, 2017-105
APPLICATIONS: Genomics research BACKGROUND: Metabolomics has been used for obtaining direct measures of metabolic activities from diverse biological systems. However, metabolomics can be limited by ambiguous metabolite identifications. Furthermore, interpretation can be limited by incomplete and inaccurate genome-based predictions of enzyme activities (e.g., gene … [Read more...] about Metabolite, Annotation and Gene Integration System (MAGI) and Software 2017-063, 2017-105