APPLICATIONS OF TECHNOLOGY: Phage engineering Cataloging and Control of phages Diagnosis and Antibiotic Discovery ADVANTAGES: No interference of the phage infection cycle No compromise of the host bacteria life cycle Enables easy amplification of the DNA “barcode” for identification, tracking and control of individual phages Standardizes the workflow … [Read more...] about Novel Methods for the Barcoding of Bacteriophages 2019-113
Research
Metabolite, Annotation and Gene Integration System (MAGI) 2017-063
APPLICATIONS: Genomics research ABSTRACT: A team of Lawrence Berkeley National Laboratory researchers including Trent Northen, Benjamin Bowen, Oliver Reubel, and Markus De Raad have developed technologies for associating metabolites with genes that enable scoring and curating compound identities based on their biological relevance, and/or using compound identities … [Read more...] about Metabolite, Annotation and Gene Integration System (MAGI) 2017-063
Improving High Value Carotenoid Astaxanthin Production 2017-033
APPLICATIONS OF TECHNOLOGY: Human health and nutrition Biofuel feedstocks Food production ADVANTAGES: More economically viable means to produce microalgae Identifies specific genes required for astaxanthin antioxidant synthesis ABSTRACT: Researchers led by Melissa Roth of Howard Hughes Medical Institute and Krishna Niyogi of the Berkeley Lab have … [Read more...] about Improving High Value Carotenoid Astaxanthin Production 2017-033
Self-Assembling Protein Nanocage decorated with Antibodies (SAPNA) 2018-075
APPLICATIONS OF TECHNOLOGY: Biopharmaceuticals Cancer immunotherapy ADVANTAGES: Capable of interchanging antibodies, therefore, multi-functional Modular, available for use by human IgG1 and rabbit IgG antibodies Potential uses increase as more monoclonal antibody products developed ABSTRACT: Researchers at the Berkeley Lab have developed a … [Read more...] about Self-Assembling Protein Nanocage decorated with Antibodies (SAPNA) 2018-075
In vitro Assembly, Adhering Cargo to Bacterial Microcompartment (BMC) Shells 2017-131, 2016-150
APPLICATIONS OF TECHNOLOGY: Enables health care, industrial and other commercial uses of protein-based bacterial organelles (bacterial microcompartments (BMCs)) ADVANTAGES: Modular system for 2- and 3-dimensional scaffolds/compartments Defined composition, atomic-resolution structure known Robust, programmable encapsulation or polyvalent display of multiple … [Read more...] about In vitro Assembly, Adhering Cargo to Bacterial Microcompartment (BMC) Shells 2017-131, 2016-150