APPLICATIONS OF TECHNOLOGY: Industrial biotechnology DNA mutation repair Genetics in organelles ADVANTAGES: Efficient, homoplasmic integrations in the mitochondrial genome Genetic change of the mtDNA without a selection marker BACKGROUND: Targeted genome engineering for mitochondria and other organelles has important implications in fungal, plant, … [Read more...] about A System for Homogenous Editing of Mitochondrial Chromosomes 2017-153
Biotechnology
High Production Titers and Rates of Tetramethyl Pyrazine 2018-101
APPLICATIONS OF TECHNOLOGY: Food (coffee) flavoring Polymer/ resin component ADVANTAGES: While Corynebacterium glutamicum has been previously reported to produce alkyl pyrazines in mixture at low levels over a long cultivation period, the high production titers and rates of enriched tetramethyl pyrazine in glutamicum in … [Read more...] about High Production Titers and Rates of Tetramethyl Pyrazine 2018-101
A CRISPR-Based and Metabolic Modeling Guided Strategy to Maximizing Indigoidine Production 2019-145
APPLICATIONS OF TECHNOLOGY: Dye and pigment (food, clothing, consumer goods) BACKGROUND: Indigodine is a natural blue pigment that retains its brightness and has direct uses in the dye and pigment industry. Notably, it shows promise as an alternative to synthetic dyes and in providing health benefits as an antioxidant … [Read more...] about A CRISPR-Based and Metabolic Modeling Guided Strategy to Maximizing Indigoidine Production 2019-145
Plant density and enhanced plant vigor estimation algorithms for high-resolution images 2019-179
APPLICATIONS OF TECHNOLOGY Agriculture BACKGROUND Farmers are seeking ways to make real-time adjustments in the field to increase productivity, however tools for estimating plant density are limited. This is true especially early in the season when the soil component is high, and visual observations tend to … [Read more...] about Plant density and enhanced plant vigor estimation algorithms for high-resolution images 2019-179
Novel Methods for the Barcoding of Bacteriophages 2019-113
APPLICATIONS OF TECHNOLOGY: Phage engineering Cataloging and Control of phages Diagnosis and Antibiotic Discovery ADVANTAGES: No interference of the phage infection cycle No compromise of the host bacteria life cycle Enables easy amplification of the DNA “barcode” for identification, tracking and control of individual phages Standardizes the workflow … [Read more...] about Novel Methods for the Barcoding of Bacteriophages 2019-113