APPLICATIONS: NIMS platform for analysis of biological molecules ADVANTAGES: More consistent, controlled NIMS chip production Does not require hydrofluoric acid Characteristics of the black silicon can be modified to alter NIMS sensitivity ABSTRACT: Trent Northen and other Berkeley Lab researchers have demonstrated a new technology for preparing black … [Read more...] about Safe Preparation of Black Silicon Substrate for Nanostructure Initiator Mass Spectrometry (NIMS) 2015-122
Biotechnology
Synthetic Production of 2-Pyrrolidone EJIB-3307
APPLICATIONS: Sustainable production of 2-Pyrrolidone used as a building block for active pharmaceutical ingredients solvent found in water-based ink solvent for membrane filters polymer precursor ADVANTAGES: Lower cost production method compared to available technologies Requires less harsh reaction conditions More environmentally-friendly … [Read more...] about Synthetic Production of 2-Pyrrolidone EJIB-3307
Converting Monomeric, Oligomeric, and Polymeric Lignin into Ionic Liquids 2015-055
APPLICATIONS: Biorefineries Ionic liqiuid manufacturing ADVANTAGES: Operates with inexpensive solvent and chemicals and uncomplicated reaction conditions Two-step synthesis with minimal purification required; could be transformed to a one-pot process ABSTRACT: Researchers led by Blake Simmons and Seema Singh at the Joint BioEnergy Institute (JBEI) have … [Read more...] about Converting Monomeric, Oligomeric, and Polymeric Lignin into Ionic Liquids 2015-055
Derivitization of Sugars into Ionic Liquids 2015-059
APPLICATIONS: Biorefineries Ionic liquid manufacturing ADVANTAGES: Potential to reduce capital costs of lignocellulosic biorefineries Improves ability to create high-valued ionic liquids from biomass ABSTRACT: Researchers led by Blake Simmons and Seema Singh at the Joint BioEnergy Institute (JBEI) have demonstrated that mucic acid – the aldaric acid of … [Read more...] about Derivitization of Sugars into Ionic Liquids 2015-059
Toaster Software: Optimizing CRISPR Technologies for Genome Editing 2016-056
APPLICATIONS: Synthetic biology Biotechnology research ADVANTAGES: Design tool for both guide RNA and for CRISPR sequences Models secondary structures ABSTRACT: Researcher Sarah Richardson of the Joint BioEnergy Institute (JBEI) has developed Toaster, a software program that designs Cas9 targeting reagents for non-human model organisms. Given a genome … [Read more...] about Toaster Software: Optimizing CRISPR Technologies for Genome Editing 2016-056