APPLICATIONS: Synthetic biology Biotechnology research ADVANTAGES: Design tool for both guide RNA and for CRISPR sequences Models secondary structures ABSTRACT: Researcher Sarah Richardson of the Joint BioEnergy Institute (JBEI) has developed Toaster, a software program that designs Cas9 targeting reagents for non-human model organisms. Given a genome … [Read more...] about Toaster Software: Optimizing CRISPR Technologies for Genome Editing 2016-056
Biotechnology
Synthesized Adipic Acid for Renewable Chemical Production 2015-106
APPLICATIONS: Renewable commodity chemical production ADVANTAGES: Environmentally friendly and sustainable pathway to commodity chemicals Reduces dependence on petroleum products The polyketide synthases can be modified to tailor make a variety of dicarboxylic acids ABSTRACT Researchers at the Joint BioEnergy Institute (JBEI) have developed a technology … [Read more...] about Synthesized Adipic Acid for Renewable Chemical Production 2015-106
Artificial Metalloproteins For Producing New Chemicals and Materials 2015-184
APPLICATIONS Catalysis for the synthesis of fine chemicals and specialty chemicals Production of new chemicals and materials Stereoselective synthesis, including enantioselective synthesis ADVANTAGES More diverse range of reaction specificity than for small-molecule catalysts Increased speed and selectivity of enzymatic reactions Creation of abiological … [Read more...] about Artificial Metalloproteins For Producing New Chemicals and Materials 2015-184
Modified Yeast Strain Imports and Utilizes Xylose as Carbon Source 2014-020
APPLICATIONS: Bulk chemicals and compounds manufacturing Biofuel production ADVANTAGES: More efficient use of starting materials More cost effective utilization of plant biomass sugars Improved profile of hexose – pentose co-utilization ABSTRACT: Researchers Jay Keasling and Aindrila Mukhopadhyay of the Joint BioEnergy Institute (JBEI) have … [Read more...] about Modified Yeast Strain Imports and Utilizes Xylose as Carbon Source 2014-020
Strong, Long-Range, Aligned Lamellar Structures for Biomedical (Synthetic Bone) and Energy Applications 2015-018
APPLICATIONS: Synthetic bone scaffolding Water purification filters Fuel cell electrodes Tissue engineering ADVANTAGES: Strong, tough, and lightweight Anisotropic properties that mimic natural materials Appropriate for many composite materials ABSTRACT: Researchers working in Berkeley Lab’s Materials Sciences Division have developed … [Read more...] about Strong, Long-Range, Aligned Lamellar Structures for Biomedical (Synthetic Bone) and Energy Applications 2015-018