ABSTRACT Berkeley Lab researchers have developed technologies to evaluate levels of the long, non-coding RNA to assess the aggressiveness of a cancer and to modulate levels of the long non-coding RNA. This invention addresses the need to identify patients with potentially metastatic tumors versus non-metastatic tumors. For more details, see Published PCT patent … [Read more...] about A Long Non-Coding RNA Expressed in Aggressive Cancer 2014-109
Biotechnology
Selective Modification of Proteins 2015-038
APPLICATIONS: Pharmaceutical therapeutics Biochemical sensors Building blocks for bio-based materials ADVANTAGES: Provides well defined method of modification Site specific Allows for control of the degree of modification ABSTRACT: Researchers at Lawrence Berkeley National Lab and the University of California, Berkeley have developed a technology … [Read more...] about Selective Modification of Proteins 2015-038
Biosynthesis Pathways for Five-Carbon Alcohol from Mevalonate 2014-135
APPLICATIONS OF TECHNOLOGY: Biological production of higher alcohols ADVANTAGES: Increased isopentenol yields in aerobic and anaerobic conditions Higher efficiency and lower costs Optimized for oxygen-limited conditions Enables production at fermentor scale Better host cell growth ABSTRACT: Researchers at the Joint BioEnergy Institute (JBEI) have … [Read more...] about Biosynthesis Pathways for Five-Carbon Alcohol from Mevalonate 2014-135
Basal Media for Culturing Epithelial Cells 2015-009
APPLICATIONS: Growing primary human epithelial cells for Pharmaceutical development Toxicology Biotechnology research ADVANTAGES: Regular and consistent formulation Superior growth for 1/12 of the price Up to 60 population doublings Can sustain long term cultures ABSTRACT: Researchers at Berkeley Lab have developed a low cost technology for growing … [Read more...] about Basal Media for Culturing Epithelial Cells 2015-009
Dominant Negative Mutations of Arabidopsis 2013-051
APPLICATIONS OF TECHNOLOGY: Plant gene expression for biofuel feedstocks biomass as feedstocks for chemical industry ABSTRACT: Xylan is one of the major polysaccharides in cellulosic biomass. There are four Arabidopsis reduced wall acetylation (RWA) genes shown to be involved in the acetylation of xylan during secondary wall biosynthesis. This invention provides … [Read more...] about Dominant Negative Mutations of Arabidopsis 2013-051