APPLICATIONS OF TECHNOLOGY: Early identification of cardiovascular disease Endothelial function assessment ADVANTAGES: Easy to operate; no need for trained technician Facilitates regular patient testing and feedback More sensitive than conventional flow-mediated vasodilation (FMD) measurement Inexpensive to manufacture Fully automated test … [Read more...] about Assessing Endothelial Function with a Standard Blood Pressure Cuff IB-2772
Biotechnology
Improved Phylogenic Microarray Design and Analysis Tools IB-2733
APPLICATIONS OF TECHNOLOGY: Monitoring water quality Identifying opportunistic and pathogenic bacteria Source tracking pollutants and pathogens Monitoring bioremediation project progress as well as naturally-occurring or introduced organisms at the site … [Read more...] about Improved Phylogenic Microarray Design and Analysis Tools IB-2733
Native Cytokines for the Treatment of Advanced Breast Cancer and Other Tumors JIB-2718
APPLICATIONS OF TECHNOLOGY: Treatment of breast and other cancers ADVANTAGES: Targets cancer cells only; does not damage normal cells Enhanced efficacy in the most aggressive breast tumors No known side effects Potential expansion to other solid tumor types ABSTRACT: Mina Bissell and colleagues at Berkeley Lab have identified and isolated several … [Read more...] about Native Cytokines for the Treatment of Advanced Breast Cancer and Other Tumors JIB-2718
Detecting and Treating Breast Cancer Resistance to EGFR Inhibitors IB-2578
ABSTRACT: Mina Bissell and colleagues at Berkeley Lab have developed therapeutic compositions and methods related to inhibition of FAM83A as well as methods of diagnosing cancer resistance to EGFR inhibitors. For details, see the issued U. S. Patent #9,303,088, available at www.uspto.gov. FOR MORE … [Read more...] about Detecting and Treating Breast Cancer Resistance to EGFR Inhibitors IB-2578
Acid-Degradeable and Bioerodible Materials JIB-2595
APPLICATIONS OF TECHNOLOGY: Drug delivery, including controlled-release formulations Vaccine and immunotherapy Gene therapy Chemotherapy Sutures, scaffolds, and implantable bulk materials Diagnosis and imaging ADVANTAGES: Site-specific delivery, accurate therapeutic targeting Payload release or degradation rate can be tuned easily—from minutes to hours to … [Read more...] about Acid-Degradeable and Bioerodible Materials JIB-2595