A subject's arm is shown positioned on the platform of the Berkeley Lab instrument. Artificial pulses are applied by the actuator and detected by an ultrasound probe. APPLICATIONS OF TECHNOLOGY: Detects cardiovascular disease (CVD) at the preclinical stage by measuring vasorelaxation Monitors the effects of statins and other drugs, vitamins, … [Read more...] about Noninvasive Detection of Preclinical Cardiovascular Disease IB-1796
Biotechnology
Prognostic for Invasive and Metastatic Cancers IB-1637
APPLICATIONS OF TECHNOLOGY: Fig.1. Down regulation of Id-1 reduces metastatic spread. Prognostic marker for invasive and metastatic cancers Therapeutic target for the suppression of invasive and metastatic cancers ADVANTAGES: Provides a highly accurate marker for invasive and metastatic cancers Identifies Id-1, a key transcriptional regulator, as a target … [Read more...] about Prognostic for Invasive and Metastatic Cancers IB-1637
Mouse Model for Common Genetic Risk Factor for Cardiovascular Disease IB-2789
APPLICATIONS OF TECHNOLOGY: Research of cardiovascular disease treatment and prevention methods ADVANTAGES: Provides new targets for coronary artery disease (CAD) and cancer drugs Enables new research avenues in Coronary artery disease and cancer Cdkn2a/b and other cyclin-dependent kinase inhibitors Disease mechanisms involving non-coding … [Read more...] about Mouse Model for Common Genetic Risk Factor for Cardiovascular Disease IB-2789
Phototriggerable Microcapsules JIB-2778
2010 R&D100 Award Winner APPLICATIONS OF TECHNOLOGY: Remote drug delivery inside the body Less invasive surgeries UV-resistant plastics and composites Self-healing plastics, polymers, paint, or concrete Master template preparation for offset printing Cosmetic and skin care items ADVANTAGES: Reaction speed, timing, and location can be … [Read more...] about Phototriggerable Microcapsules JIB-2778
Library of Plasmids to Control Gene Expression Levels EIB-2792
APPLICATIONS OF TECHNOLOGY: Biofuel production Pharmaceutical and chemical production Biological research involving gene expression ADVANTAGES: Enables control over gene expression Applicable with any genes lacking 4 particular restriction sites ABSTRACT: Taek Soon Lee and colleagues at the Joint BioEnergy Institute (JBEI) have developed a technology that … [Read more...] about Library of Plasmids to Control Gene Expression Levels EIB-2792