APPLICATIONS: Development of genetically modified crops with increased yield, pest resistance, and improved nutritional content Development of crops with increased resilience to climate change-induced environmental stresses Engineering crops for biofuel production by optimizing growth rates and increasing lipid or carbohydrate content ADVANTAGES: Transform … [Read more...] about Agrobacterium-Mediated Plant and Fungal Transformation with Refactored Virulence Plasmids 2021-072
Biotechnology
Catalytic Depolymerization of Lignin via Metal Catalysts 2020-148
APPLICATIONS: Feedstocks for the production of biofuels and bioproducts ADVANTAGES: Compatible with downstream processes Supported (multi)metallic-nanoparticle (NP) catalysts (lower loading) Improved process economics via catalytic reusability Tunable, allowing for precise control over the production of desired compounds BACKGROUND: Lignin is the … [Read more...] about Catalytic Depolymerization of Lignin via Metal Catalysts 2020-148
One-Pot Golden Gate Cloning via Methylation and Chemically Modified Assisted Tailorable Ends (McMaster) 2023-035
APPLICATIONS OF TECHNOLOGY: DNA Assembly & Cloning Biological Research Sequencing Protein Expression ADVANTAGES: One pot cloning, regardless of internal restriction sites Assembly using various restriction enzymes BACKGROUND: Golden Gate assembly is the preferred DNA assembly technique for repetitive DNA elements and secondary structure, as … [Read more...] about One-Pot Golden Gate Cloning via Methylation and Chemically Modified Assisted Tailorable Ends (McMaster) 2023-035
Genetically Modified Host Cells for Improved Polyketide Production 2022-152
APPLICATIONS OF TECHNOLOGY: High-value products using methylmalonyl-CoA as substrate: Erythromycin (antibiotic) and spinosyn (insecticide) Germicidin, which has significant inhibitory activity on hexokinase which is expressed at a high level in cancer cells Novel recyclable materials Flavors and fragrances Commodity or specialty chemicals ADVANTAGES: … [Read more...] about Genetically Modified Host Cells for Improved Polyketide Production 2022-152
Metabolic engineering of Issatchenkia orientalis for citramalate production used in PMMA Acrylic Glass 2023-056
APPLICATIONS OF TECHNOLOGY: Production of citramalate, a precursor for polymethyl methacrylate (PMMA) polymers. PMMA is used in electronic device screens, automotive plastics, glazing, building piping, and insulation ADVANTAGES: Increases the achievable carbon yields of select organic acids Consumes less energy and generates less toxic waste than current … [Read more...] about Metabolic engineering of Issatchenkia orientalis for citramalate production used in PMMA Acrylic Glass 2023-056