APPLICATIONS OF TECHNOLOGY: Microfluidics Pico- and nano-liter dispensing devices Droplet microfluidics used for genomic and sequencing sample preparation and analysis ADVANTAGES: Minimizes waste Reduces costs Eliminates the additional steps for dispensing the desired sized droplets on chip Prevents the evaporation and merging of droplets Enables … [Read more...] about Contactless Loading to a Microfluidic Chip 2019-078
Synthetic Biology Tools and Software
The CORAL Framework for FAIR Data Management and Analysis 2019-123
APPLICATIONS OF TECHNOLOGY: Moderately sized organizations or companies Multi-lab research collaborations ADVANTAGES: Low cost Ease of adding new data types Models different variations of the same conceptual data types Adheres to all four of the FAIR principles (see below) ABSTRACT: Researchers at Berkeley Lab have designed and prototyped a … [Read more...] about The CORAL Framework for FAIR Data Management and Analysis 2019-123
ART: A machine learning Automated Recommendation Tool for guiding synthetic biology 2020-011
APPLICATIONS: Companies performing synthetic biology/metabolic engineering ADVANTAGES: Demonstrated high predictive accuracy Shorter strain development times TECHNOLOGY OVERVIEW: Researchers at Berkeley Lab’s Joint BioEnergy Institute and the Agile BioFoundry have developed a tool that uses machine learning to make further advancements in the field … [Read more...] about ART: A machine learning Automated Recommendation Tool for guiding synthetic biology 2020-011
Novel fungal Autoinducible Expression System 2019-174
APPLICATIONS OF TECHNOLOGY: Biotech and pharmaceutical companies Commodity chemicals Potential to improve yield, titer, process efficiency and process economics for companies producing a variety of materials, chemicals and fuels in yeast cell factories ADVANTAGES: Useful in any media composition. Has value in both systems that produce high value compounds and … [Read more...] about Novel fungal Autoinducible Expression System 2019-174
Metabolite, Annotation and Gene Integration System (MAGI) and Software 2017-063, 2017-105
APPLICATIONS: Genomics research BACKGROUND: Metabolomics has been used for obtaining direct measures of metabolic activities from diverse biological systems. However, metabolomics can be limited by ambiguous metabolite identifications. Furthermore, interpretation can be limited by incomplete and inaccurate genome-based predictions of enzyme activities (e.g., gene … [Read more...] about Metabolite, Annotation and Gene Integration System (MAGI) and Software 2017-063, 2017-105