APPLICATIONS: Preparation of biological samples for electron microscopy ADVANTAGES: Enables consistent and reliable production of samples Thickness of cryo-EM specimens is uniform across the grid Facilitates the production of extremely thin samples Potentially damaging sample evaporation not required ABSTRACT: Researchers at Berkeley Lab have … [Read more...] about Consistent, Reliable Preparation of Cryo-EM Specimens 2015-108
Electron microscopy
High-Affinity Specimen Support Film for Electron Microscopy 2015-002
APPLICATIONS: Sample preparation for electron microscopy of biological macromolecules ADVANTAGES: Protective, soluble coating ensures long shelf life, enabling commercial distribution Employs streptavidin monolayer-crystals for a combination of high affinity and specificity when binding macromolecules Affinity binding to the substrate prevents unwanted … [Read more...] about High-Affinity Specimen Support Film for Electron Microscopy 2015-002
Electrically Integrated Graphene on Silicon Nitride Liquid Flow Cells for High Resolution TEM 2014-129
APPLICATIONS OF TECHNOLOGY: TEM for the study of electrochemical processes to advance Catalysis Battery and fuel cell technologies Targeted drug delivery Nanotechnology ADVANTAGES: Atomic resolution and contrast Diminished alteration of samples Simple and easy to use; little to no assembly by final user Reusable ABSTRACT: A Berkeley Lab … [Read more...] about Electrically Integrated Graphene on Silicon Nitride Liquid Flow Cells for High Resolution TEM 2014-129
BioSig3D: Software for Integrated Imaging and Profiling of 3D Cell Culture Models 2013-177, 2014-024
APPLICATIONS: Analysis of 3D cell culture model systems Oncology research and drug development Couples novel image analysis algorithms with 3D microscopy ADVANTAGES: End-to-end solution -- from assay to bioinformatics Enables 3D visualization and analysis of 3D spatial data Quantifies subcellular morphometric indices and corresponding molecular endpoints, on … [Read more...] about BioSig3D: Software for Integrated Imaging and Profiling of 3D Cell Culture Models 2013-177, 2014-024
Graphene Membranes for Nanometer-scale Lithography and Single Atom Resolution TEM Imaging , 2502 IB-2501
APPLICATIONS OF TECHNOLOGY: Using electron-beam induced deposition (EBID) on graphene membranes to create nano-scale doping patterns for electronic circuits lithography etch masks diffraction gratings (for monochromators, spectrometers, wavelength division multiplexing devices, optical pulse compressing devices and other optical devices) Investigating the … [Read more...] about Graphene Membranes for Nanometer-scale Lithography and Single Atom Resolution TEM Imaging , 2502 IB-2501