ABSTRACT: Researchers at Berkeley Lab led by Hoi-Ying Holman have developed technologies for measurement, visualization, and analysis of chemical dynamics in living cells or tissues for diagnostic pathology. Devices can be open- or closed-channel microfluidic membrane devices for long-term IR spectroscopy of live adherent cells and ultimately for rapidly identifying … [Read more...] about Spectroscopic Imaging and Analysis of Live Cells 2015-077
Spectroscopy and Microscopy
Increased Specificity and Sensitivity to Detect Targeted Metabolites using NIMS 2017-051
APPLICATIONS OF TECHNOLOGY: Biological and chemical assays Selective metabolite analysis ADVANTAGES: Increased sensitivity to detect targeted metabolites High selectivity to targeted metabolites Extremely sensitive and non-destructive analytical technique ABSTRACT: Nanostructure-initiator Mass Spectrometry (NIMS) is a surface-based mass … [Read more...] about Increased Specificity and Sensitivity to Detect Targeted Metabolites using NIMS 2017-051
Optical-Cavity Phase Plate for Controllable, Stable Phase Shift in TEM and Cryo-EM Applications 2017-080
APPLICATIONS OF TECHNOLOGY: Biological research using high resolution cryogenic electron microscopy (cryo-EM) Hard-matter material characterization Other forms of research using transmission electron microscopy (TEM) ADVANTAGES: Ensures data of equally high quality for entire data collection period Equally useful for radiation-tolerant and … [Read more...] about Optical-Cavity Phase Plate for Controllable, Stable Phase Shift in TEM and Cryo-EM Applications 2017-080
Specialized Diamond Materials for NMR Signal Enhancement 2016-156
APPLICATIONS OF TECHNOLOGY: Materials characterization for commercial manufacturing quality control development of unique materials research and education ADVANTAGES: Enables smaller, more versatile characterization devices Can be used to characterize almost any kind of material ABSTRACT: Berkeley Lab’s Alex Pines has led a team of researchers in … [Read more...] about Specialized Diamond Materials for NMR Signal Enhancement 2016-156
Ultrafast Optical Pulse Combining Lasers 2016-052
APPLICATIONS OF TECHNOLOGY: Laser-based accelerator facilities for scientific research Short pulse micromachining ADVANTAGES: Enables fiber lasers to be used in high energy ultrafast applications Can be added to existing laser technology without affecting size or reliability Considerably reduces complexity of the combining optics Decreases the negative … [Read more...] about Ultrafast Optical Pulse Combining Lasers 2016-052