APPLICATIONS OF TECHNOLOGY: Biological and chemical assays Selective metabolite analysis ADVANTAGES: Increased sensitivity to detect targeted metabolites High selectivity to targeted metabolites Extremely sensitive and non-destructive analytical technique ABSTRACT: Nanostructure-initiator Mass Spectrometry (NIMS) is a surface-based mass … [Read more...] about Increased Specificity and Sensitivity to Detect Targeted Metabolites using NIMS 2017-051
Spectroscopy and Microscopy
Optical-Cavity Phase Plate for Controllable, Stable Phase Shift in TEM and Cryo-EM Applications 2017-080
APPLICATIONS OF TECHNOLOGY: Biological research using high resolution cryogenic electron microscopy (cryo-EM) Hard-matter material characterization Other forms of research using transmission electron microscopy (TEM) ADVANTAGES: Ensures data of equally high quality for entire data collection period Equally useful for radiation-tolerant and … [Read more...] about Optical-Cavity Phase Plate for Controllable, Stable Phase Shift in TEM and Cryo-EM Applications 2017-080
Specialized Diamond Materials for NMR Signal Enhancement 2016-156
APPLICATIONS OF TECHNOLOGY: Materials characterization for commercial manufacturing quality control development of unique materials research and education ADVANTAGES: Enables smaller, more versatile characterization devices Can be used to characterize almost any kind of material ABSTRACT: Berkeley Lab’s Alex Pines has led a team of researchers in … [Read more...] about Specialized Diamond Materials for NMR Signal Enhancement 2016-156
Ultrafast Optical Pulse Combining Lasers 2016-052
APPLICATIONS OF TECHNOLOGY: Laser-based accelerator facilities for scientific research Short pulse micromachining ADVANTAGES: Enables fiber lasers to be used in high energy ultrafast applications Can be added to existing laser technology without affecting size or reliability Considerably reduces complexity of the combining optics Decreases the negative … [Read more...] about Ultrafast Optical Pulse Combining Lasers 2016-052
ARGO: Peptide Barcoding for Genomic Discovery 2015-123
APPLICATIONS OF TECHNOLOGY: Biomanufacturing of enzymes Enzyme research ADVANTAGES: Rapid discovery of the function of genes Capable of multiplexing Ultra-high-throughput ABSTRACT: Researchers at Berkeley Lab led by Trent Northen have developed the ARGO (Assignment of the Reactions of Gene products in Organisms) platform, an efficient and scalable … [Read more...] about ARGO: Peptide Barcoding for Genomic Discovery 2015-123