APPLICATIONS: Preparation of biological samples for electron microscopy ADVANTAGES: Enables consistent and reliable production of samples Thickness of cryo-EM specimens is uniform across the grid Facilitates the production of extremely thin samples Potentially damaging sample evaporation not required ABSTRACT: Researchers at Berkeley Lab have … [Read more...] about Consistent, Reliable Preparation of Cryo-EM Specimens 2015-108
Spectroscopy and Microscopy
High-Affinity Specimen Support Film for Electron Microscopy 2015-002
APPLICATIONS: Sample preparation for electron microscopy of biological macromolecules ADVANTAGES: Protective, soluble coating ensures long shelf life, enabling commercial distribution Employs streptavidin monolayer-crystals for a combination of high affinity and specificity when binding macromolecules Affinity binding to the substrate prevents unwanted … [Read more...] about High-Affinity Specimen Support Film for Electron Microscopy 2015-002
Electrically Integrated Graphene on Silicon Nitride Liquid Flow Cells for High Resolution TEM 2014-129
APPLICATIONS OF TECHNOLOGY: TEM for the study of electrochemical processes to advance Catalysis Battery and fuel cell technologies Targeted drug delivery Nanotechnology ADVANTAGES: Atomic resolution and contrast Diminished alteration of samples Simple and easy to use; little to no assembly by final user Reusable ABSTRACT: A Berkeley Lab … [Read more...] about Electrically Integrated Graphene on Silicon Nitride Liquid Flow Cells for High Resolution TEM 2014-129
AIRLAB-MS for Analysis of Complex Biological Systems Under Native Conditions 2014-084
APPLICATIONS OF TECHNOLOGY: Biofuel development Research – pharmaceutical, medical, agricultural ADVANTAGES: Samples biological systems under native conditions with no preparation Integrates laser ablation sampling and mass spectrometry with IR microscopy High transfer efficiency of ~50% Spatially resolved chemical composition ABSTRACT: Berkeley … [Read more...] about AIRLAB-MS for Analysis of Complex Biological Systems Under Native Conditions 2014-084
Active Cryogenic Electronic Envelope 2014-038
The Berkeley Lab Active Cryogenic Electronic Envelope allows conventional front-end electronics, such as enhanced metal-oxide semiconductors, to work inside cryostats at temperatures as low as 4.2K without the expense of custom-made electronics. APPLICATIONS OF TECHNOLOGY: Instrumentation for cryogenic vessels used in Medical diagnostic equipment Aerospace … [Read more...] about Active Cryogenic Electronic Envelope 2014-038