APPLICATIONS OF TECHNOLOGY: Medical diagnostics and therapeutic classification Biotechnology research and development Developmental biology ADVANTAGES: Enables metabolic flux imaging, not possible by other techniques Overcomes quantification challenges in mass spectrometry imaging ABSTRACT: Using time dependent isotopic labeling and mass spectrometry … [Read more...] about Nanostructure Initiator Mass Spectrometry (NIMS) Flux Imaging JIB-3066
Spectroscopy and Microscopy
NIMS Skin Touch Chemical Imaging IB-2958
APPLICATIONS OF TECHNOLOGY: Security / Identification Criminal investigation Biometric identification Medical history Medical diagnosis Testing product efficiency Cosmetics development ADVANTAGES: Enhanced detection of skin-surface chemicals, microbes Non-invasive test for endogenous metabolites Deeper understanding of an individual’s past … [Read more...] about NIMS Skin Touch Chemical Imaging IB-2958
Multinozzle Emitter Array (MEA) for On-chip Mass Spectrometry IB-2977
APPLICATIONS OF TECHNOLOGY: In vitro diagnostics Biopharmaceutical R&D Systems biology laboratory research Single-cell “omics” Lab-on-a-chip analyses Food safety testing Environmental monitoring ADVANTAGES: Robust and scalable silicon fabrication technologies High-throughput multiplexing, i.e., processing multiple analytes sequentially … [Read more...] about Multinozzle Emitter Array (MEA) for On-chip Mass Spectrometry IB-2977
High Throughput Nanoparticle Delivery to the Cytosol of Living Cells IB-2849
APPLICATIONS OF TECHNOLOGY: Basic and applied research on intracellular processes Biological imaging Medical diagnostics Pharmaceutical development ADVANTAGES: Rapid cytosolic delivery within a few hours of incubation Mere picomolar concentrations of nanoparticles required for labeling Amenable to most nanoparticle formulations and cell/tissue … [Read more...] about High Throughput Nanoparticle Delivery to the Cytosol of Living Cells IB-2849
BioSig3D: Software for Integrated Imaging and Profiling of 3D Cell Culture Models 2013-177, 2014-024
APPLICATIONS: Analysis of 3D cell culture model systems Oncology research and drug development Couples novel image analysis algorithms with 3D microscopy ADVANTAGES: End-to-end solution -- from assay to bioinformatics Enables 3D visualization and analysis of 3D spatial data Quantifies subcellular morphometric indices and corresponding molecular endpoints, on … [Read more...] about BioSig3D: Software for Integrated Imaging and Profiling of 3D Cell Culture Models 2013-177, 2014-024